Richard Palmiter
Richard Deforest Palmiter (born April 5, 1942 in Poughkeepsie , New York ) is an American biochemist and molecular geneticist at the University of Washington .
Palmiter earned a bachelor's degree in zoology from Duke University in 1964 and a Ph.D. in 1968 with the thesis Regulation of the Production of Lactose in the Mammary Gland of the Mouse. with Norman K. Wessells at Stanford University . Pamlmiter worked as a postdoctoral fellow with Fotis Kafatos and Robert T. Schimke . Since 1974 he has been a member of the faculty at the University of Washington in Seattle , where he is now Professor of Biochemistry . Since 1976 Palmiter has also been doing research for the Howard Hughes Medical Institute (HHMI).
Palmiter made a name for himself in various areas of molecular biology and animal physiology . Early work dealt with the regulation of transcription by steroid hormones or with the regulation and function of metallothioneins . He is best known for his work with Ralph L. Brinster , which led to the development of transgenic mice . Brinster and Palmiter developed thousands of different transgenic mice to answer different biological questions.
Palmiter is currently working on neural circuits that influence behavior, especially appetite . By means of various manipulations (including recently also methods of optogenetics ), neurons are identified and examined for their interconnection and function, which express certain proteins , including AgRP and CGRP . Palmiter et al. Gained important insights into the role of the CGRP-expressing neurons in the parabrachial nucleus for taste and fear or the memory of them. Previous work looked at the role of GABA , NPY or zinc in appetite and feeding behavior.
Palmiter became a Fellow of the American Association for the Advancement of Science in 1987 and a member of both the National Academy of Sciences and the American Academy of Arts and Sciences in 1988 . In 1994 he was awarded the Prix Charles-Léopold Mayer together with Ralph L. Brinster .
literature
- Brian Shmaefsky: Biotechnology 101 . Greenwood Publishing Group, ISBN 978-0-313-33528-0 , pp. 188 ( limited preview in Google Book search).
Web links
- Richard Palmiter at the University of Washington (washington.edu)
- Richard D. Palmiter, PhD at the Michael J. Fox Foundation (michaeljfox.org)
- Life data, publications and academic pedigree of Richard DeForest Palmiter at academictree.org, accessed on July 6, 2018.
- Richard DeForest Palmiter, Ph.D. at neurotree.org (redundant to academictree.org)
Individual evidence
- ↑ Richard D. Palmiter, PhD. In: hhmi.org. Retrieved July 7, 2018 .
- ↑ Palmiter, Richard D. In: aaas.org. February 9, 2018, accessed July 6, 2018 .
- ↑ Richard Palmiter. In: nasonline.org. Accessed July 6, 2018 .
- ↑ Book of Members 1780 – present, Chapter P. (PDF; 649 kB) In: American Academy of Arts and Sciences (amacad.org). Accessed July 6, 2018 .
- ^ Prix Charles-Léopold Mayer. List of award winners at academie-sciences.fr; Retrieved on July 6, 2018 (PDF; 1.8 MB, as of 2014, French).
| personal data | |
|---|---|
| SURNAME | Palmiter, Richard |
| ALTERNATIVE NAMES | Palmiter, Richard D .; Palmiter, Richard Deforest; Palmiter, Richard DeForest |
| BRIEF DESCRIPTION | American biochemist and molecular geneticist |
| DATE OF BIRTH | April 5, 1942 |
| PLACE OF BIRTH | Poughkeepsie , New York |