Sin Nombre Virus

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Sin Nombre Virus
Sin Nombre virus Hanta TEM 1137 lores.jpg

Sin Nombre Virus

Systematics
Classification : Viruses
Area : Riboviria
Empire : Orthornavirae
Phylum : Negarnaviricota
Subphylum : Polyploviricotina
Class : Ellioviricetes
Order : Bunyavirales
Family : Hantaviridae
Genre : Orthohantavirus
Type : Sin Nombre Virus
Taxonomic characteristics
Genome : (-) ss RNA segmented
Baltimore : Group 5
Symmetry : helical
Cover : available
Scientific name
Sin Nombre orthohantavirus
Short name
SNV
Left
Sin Nombre Virus after budding from a Vero cell

The Sin Nombre Virus ( scientifically Sin Nombre orthohantavirus , SNV, obsolete Four Corner Virus ) belongs to the genus of the Hantaviruses (family of the Hantaviridae ).

The name comes from Spanish and means virus without a name .

construction

It is an enveloped virus whose natural host is the deer mouse . The virus can get into the human lungs via the air in the form of an aerosol via their dried excrement .

Genome

The genome consists of three segments of linear, single-stranded RNA with negative polarity , which are associated with the capsid proteins and arranged in a spiral.

Pathology and epidemiology

The Sin Nombre virus is, among other things, the cause of the hantavirus-associated cardiopulmonary syndrome (HPS / HCPS). The mortality from this disease is between 30 and 40%.

For the first time, after an unusually wet spring in 1993, a regionally limited epidemic occurred in the southwestern United States (hence the original name Four Corner Virus ). Of the 48 mostly young patients, 27 (55%) died. Between 1993 and 2015, there were a total of 659 illnesses in the United States with 235 deaths.

literature

  • Medical microbiology, Thieme Verlag

Web links

Individual evidence

  1. ICTV Master Species List 2018b.v2 . MSL # 34, March 2019
  2. a b ICTV: ICTV Taxonomy history: Akabane orthobunyavirus , EC 51, Berlin, Germany, July 2019; Email ratification March 2020 (MSL # 35)