|Molecular formula||C 21 H 32 N 2 O|
|External identifiers / databases|
|Molar mass||328.49 g · mol -1|
|As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .|
Area of application and mode of action
Stanozolol is mainly used in veterinary medicine , especially in domestic dogs , house cats and horses to stimulate appetite , gain weight and build muscle ( anabolic effect). Finished medicinal products are no longer on the market in most European countries. In human medicine, stanozolol can be indicated in the long-term treatment or prophylaxis of hereditary Quincke edema ( hereditary angioedema ). No finished medicinal products are available here either.
The anabolic property makes stanozolol useful as a doping agent . It became famous at the 1988 Olympic Games when the athlete Ben Johnson was convicted of taking stanozolol. Despite its relationship to dihydrotestosterone, stanozolol is only weakly androgenic and moderately anabolic. Stanozolol cannot convert to estrogen in the human body . A stanozolol derivative is Furazabol .
In body building , stanozolol is used before competitions and in the diet phase, as it enables the build-up of lean muscle mass even in negative calorie phases. The increase in strength is moderate compared to other steroids, but steady.
Stanozolol has a negative effect on blood lipid levels like no other steroid. According to a study by the drug manufacturer Zambon SA (Spain / Barcelona), which sells the stanozolol-containing drug Winstrol , a dose of 50 mg every 48 hours can worsen the level of high density lipoprotein (HDL) by up to 99%. A low HDL value represents an increased risk of cardiovascular diseases up to and including myocardial infarction , since blood lipids are deposited in the arteries and can clog them. The risk is also increased when taking Stanozol in combination with Trenbolone or Boldenone .
Stanozolol has a methyl group in the alpha position on the C17 and is therefore, like other C17-alkylated steroids, harmful to the liver , especially when administered orally (tablets). Stanozolol, when taken regularly, dries out the joints, which can lead to pain and long-term damage.
In Germany, possession of non-small amounts of stanozolol (from 150 mg according to the Doping Substance Amount Ordinance as of June 2016) for doping purposes is punishable under the Anti-Doping Act .
- Entry on stanozolol at Vetpharm, accessed on August 5, 2012.
- Stanozolol data sheet from Sigma-Aldrich , accessed on October 9, 2016 ( PDF ).
- K. Hardtke et al. (Ed.): Commentary on the European Pharmacopoeia Ph. Eur. 6.3, Stanozolol. Loose-leaf collection, 33rd delivery 2009, Wissenschaftliche Verlagsgesellschaft Stuttgart.
- The Black Book - Anabolic Steroids , 2007. Page 467/468 ISBN 978-3-00-020944-4 .