2- tert- butylhydroquinone

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Structural formula
Structural formula of 2-tert-butylhydroquinone
General
Surname 2- tert- butylhydroquinone
other names
  • tert -butylhydroquinone
  • TBHQ
  • 2- tert- butyl-1,4-benzenediol
  • E  319
  • TBHQ ( INCI )
Molecular formula C 10 H 14 O 2
Brief description

light brown solid with a faint odor

External identifiers / databases
CAS number 1948-33-0
EC number 217-752-2
ECHA InfoCard 100.016.139
PubChem 16043
ChemSpider 15235
DrugBank DB07726
Wikidata Q662443
properties
Molar mass 166.22 g mol −1
Physical state

firmly

density

1.05 g cm −3

Melting point

127-129 ° C

boiling point

295 ° C

solubility
  • practically insoluble in water
  • Easily soluble in fats and oils
safety instructions
GHS labeling of hazardous substances
07 - Warning 09 - Dangerous for the environment

Caution

H and P phrases H: 302-317-319-410
P: 273-280-302 + 352-305 + 351 + 338
Toxicological data

700 mg kg −1 ( LD 50 ,  rat ,  oral )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

2- tert -Butylhydroquinone is a chemical compound from the group of hydroquinones .

properties

2- tert -Butylhydroquinone is a flammable, light brown crystalline solid with a faint odor, which is practically insoluble in water.

use

2- tert -Butylhydroquinone is often used as a preservative for fatty cosmetics (concentration 0.1 to 1.0%) and, in the USA, also for high-fat foods (especially fish, lard and animal fats). It is often used in combination with certain antioxidants to support the effects. It is approved in the EU as a food additive with the number E 319 with a maximum quantity restriction of up to 200 milligrams per kilogram of fat as an antioxidant for food. In low concentrations it shows cytoprotective properties, while at higher concentrations it shows cytotoxic behavior. It is used in research to investigate the inactivation of barotolerant strains of Listeria monocytogenes and Escherichia coli .

safety instructions

The permitted daily dose was set by the JECFA at up to 0.7 mg / kg.

Individual evidence

  1. ↑ Entry on E 319: Tertiary-butyl hydroquinone (TBHQ) in the European database for food additives, accessed on June 28, 2020.
  2. ↑ Entry on TBHQ in the CosIng database of the EU Commission, accessed on May 22, 2020.
  3. ↑ a b c d e f g h i j Entry on 2-tert-butylhydroquinone in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .
  4. ↑ a b EFSA: Opinion of the Scientific Panel on food additives, flavors, processing aids and materials in contact with food (AFC) on a request from the Commission related to tertiary-Butylhydroquinone (TBHQ). In: EFSA Journal. 2, 2004, p. 84, doi : 10.2903 / j.efsa.2004.84 .
  5. ^ A b Gerhard Eisenbrand, Peter Schreier, Alfred Hagen Meyer: RÖMPP Lexikon Lebensmittelchemie, 2nd edition, 2006 . Georg Thieme Verlag, 2014, ISBN 3-13-179282-5 , p. 161 ( limited preview in Google Book search).
  6. ↑ Bernd Leitenberger: Additives and E numbers All additives and E numbers as well as the legal basis explained . BoD - Books on Demand, 2013, ISBN 978-3-8482-5291-6 , pp. 62 ( limited preview in Google Book search).
  7. ↑ Zusatzstoffe-online.de: Tertiary butyl hydroquinone (TBHQ)
  8. ↑ Data sheet tert-butylhydroquinone, 97% from Sigma-Aldrich , accessed on October 5, 2015 ( PDF ).