Tolnaftat
Structural formula | ||||||||||||||||||||||
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General | ||||||||||||||||||||||
Non-proprietary name | Tolnaftat | |||||||||||||||||||||
other names |
O -naphthalen-2-yl [methyl- (3-methylphenyl) amino] methanthioate ( IUPAC ) |
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Molecular formula | C 19 H 17 NOS | |||||||||||||||||||||
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Drug information | ||||||||||||||||||||||
ATC code | ||||||||||||||||||||||
Drug class | ||||||||||||||||||||||
properties | ||||||||||||||||||||||
Molar mass | 307.41 g · mol -1 | |||||||||||||||||||||
Physical state |
firmly |
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Melting point |
111 ° C |
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safety instructions | ||||||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Tolnaftate is a drug that is used as a topical antifungal agent . It is a thiocarbamate .
application areas
Tolnaftate has fungicidal effects on dermatophytes , but is ineffective against yeasts .
effect
It inhibits the sterol - synthesis by the enzyme squalene epoxidase blocked.
swell
- C.-J. Estler (founder) u. H. Schmidt (Ed.): Pharmacology and Toxicology . 6th edition, Schattauer, 2007, p. 843.
Individual evidence
- ↑ entry to tolnaftate in DrugBank the University of Alberta .
- ↑ a b Tolnaftate data sheet at Sigma-Aldrich , accessed on June 16, 2011 ( PDF ).
Trade names
Tinatox (D), as well as a generic (D)
Undex (CH)