Tolnaftat

Structural formula
General
Non-proprietary name	Tolnaftat
other names	O -naphthalen-2-yl [methyl- (3-methylphenyl) amino] methanthioate ( IUPAC )
Molecular formula	C 19 H 17 NOS
External identifiers / databases
CAS number 2398-96-1 EC number 219-266-6 ECHA InfoCard 100.017.516 PubChem 5510 ChemSpider 5309 DrugBank DB00525 Wikidata Q415238
Drug information
ATC code	D01 AE18
Drug class	Antifungal agent
properties
Molar mass	307.41 g · mol -1
Physical state	firmly
Melting point	111 ° C
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed GHS labeling of hazardous substances no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Tolnaftate is a drug that is used as a topical antifungal agent . It is a thiocarbamate .

application areas

Tolnaftate has fungicidal effects on dermatophytes , but is ineffective against yeasts .

effect

It inhibits the sterol - synthesis by the enzyme squalene epoxidase blocked.

swell

• C.-J. Estler (founder) u. H. Schmidt (Ed.): Pharmacology and Toxicology . 6th edition, Schattauer, 2007, p. 843.

Individual evidence

1. ↑ entry to tolnaftate in DrugBank the University of Alberta .
2. ↑ ^{a b} Tolnaftate data sheet at Sigma-Aldrich , accessed on June 16, 2011 ( PDF ).

Trade names

Monopreparations

Tinatox (D), as well as a generic (D)

Combination preparations

Undex (CH)

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !