Xiaodong Wang

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Xiaodong Wang ( Chinese  王曉東  /  王晓东 , Pinyin Wāng Xiǎodōng ; * 1963 in Wuhan , People's Republic of China ) is an American biochemist and molecular biologist .

Life

Wang graduated from Peking University of Education with a degree in biology in 1984 and a Ph.D. from Richard Padgett of the University of Texas Southwestern Medical Center in 1991 from Richard Padgett. in biochemistry . As a postdoctoral fellow , he worked with Nobel Prize winners Michael S. Brown and Joseph L. Goldstein on cholesterol regulation by the protein SREBP . In 1995 Wang received his first professorship (Assistant Professor) and his own laboratory at the Department of Biochemistry at Emory University in Atlanta , Georgia , where he began to study apoptosis and its regulation intensively . In 1996, Wang returned to the University of Texas Southwestern Medical Center under the new head of biochemistry there, Steve McKnight . Since 1997, Wang has also been doing research for the Howard Hughes Medical Institute .

Today (as of 2012) Wang is doing research at the National Institute of Biological Sciences in Beijing , of which he is co-director. Wang is married.

Act

Wang is considered a pioneer in researching the effector mechanisms of apoptosis , which take place in the cytosol along the mitochondria . Wang identified and characterized the apoptosome complex of cytochrome c , apaf-1 and caspase -9, which causes cell death. In addition, Wang discovered other apoptosis regulator proteins , including DFF , EndoG and SMAC . Wang's research showed a metabolic pathway in and out of the mitochondrion and nucleus .

Awards (selection)

literature

  • Nick Zagorski: Profile of Xiaodong Wang. In: Proceedings of the National Academy of Sciences. 2006 January 3; 103 (1): 7-9. doi: 10.1073 / pnas.0509187103

Web links

Individual evidence

  1. ↑ In 2004 he received the NAS Award in Molecular Biology , which can only be given to US citizens.
  2. ↑ Eli Lilly Award in Biological Chemistry , winner 1935 to 2012 (PDF; 46 kB); Retrieved February 23, 2012
  3. ↑ http://www.welch1.org/awards/norman-hackerman-award-in-chemical-research/past-recipients
  4. ^ NAS Award in Molecular Biology. In: nasonline.org. Retrieved January 13, 2016 .
  5. ↑ The Shaw Laureate in Life Science and Medicine 2006 at shawprize.org; Retrieved February 19, 2012
  6. ^ Richard Lounsbery Award at the National Academy of Sciences (nasonline.org); Retrieved February 23, 2012
  7. ↑ EMBO enlarges its membership for 50th anniversary. Press release from May 8, 2014 at the Science Information Service (idw-online.de)
  8. ↑ International König Faisal Prize 2020
personal data
SURNAME Wang, Xiaodong
BRIEF DESCRIPTION American biochemist and molecular biologist
DATE OF BIRTH 1963
PLACE OF BIRTH Wuhan , People's Republic of China