4-pyrimidinone

Structural formula
General
Surname	4-pyrimidinone
other names	4-hydroxypyrimidine 4-pyrimidinol 4 (3H) -pyrimidinone
Molecular formula	C 4 H 4 N 2 O
Brief description	white solid
External identifiers / databases
CAS number 51953-17-4 EC number 257-545-4 ECHA InfoCard 100.052.297 PubChem 20695 ChemSpider 19489 Wikidata Q17572767
properties
Molar mass	96.09 g mol −1
Physical state	firmly
Melting point	164-167 ° C
solubility	soluble in water
safety instructions
GHS labeling of hazardous substances no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

4-pyrimidinone is a chemical compound from the group of pyrimidines . The compound is part of the basic structure of the nucleobase isocytosine . It is also found as a partial structure in mizolastine .

Extraction and presentation

4-Pyrimidinones can be obtained, among other things, by reacting a β-ketoester with thiourea , followed by desulfurization of the resulting product using Raney nickel .

properties

4-pyrimidinone is a white solid. In the spectrum of the compound instructions exist on an amide - tautomer .

Individual evidence

1. ↑ ^{a b c d e f g} Data sheet 4-Pyrimidinone, 98% from AlfaAesar, accessed on August 9, 2014 ( PDF )(JavaScript required) .
2. ↑ Patent application EP0326389A2 : Process for preparing 4-hydroxypyrimidine. Applied January 26, 1989 , published August 2, 1989 , Applicant: Ube Industries , Inventor: Kikuo C / O Ube Research Laboratory Ataka, Kiyoshi C / O Ube Research Laboratory Omori. ‌
3. ↑ Eberhard Breitmaier, Günther Jung: Organic chemistry . Georg Thieme Verlag, 2005, p. 641 ( limited preview in Google Book search).