Agmatine
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| General | ||||||||||||||||||||||
| Surname | Agmatine | |||||||||||||||||||||
| other names |
2- (4-aminobutyl) guanidine |
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| Molecular formula | C 5 H 14 N 4 | |||||||||||||||||||||
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| properties | ||||||||||||||||||||||
| Molar mass | 130.19 g mol −1 | |||||||||||||||||||||
| Physical state |
firmly |
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| Melting point |
101.5-103 ° C |
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| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | ||||||||||||||||||||||
Agmatine is a guanidine compound. It is the decarboxylation product of the amino acid arginine and an intermediate in the putrescine biosynthesis from arginine, which is particularly widespread in plants . Agmatine is being discussed as a possible neurotransmitter that is synthesized in the brain and stored in the synaptic vesicles .
Natural occurrences are known from ergot , the daisy family Ambrosia artemisifolia , the sea anemone Anthopleura japonica and herring seeds.
History
The name Agmatine was given in 1910 by Albrecht Kossel , a German physician and physiologist who was able to detect this substance in herring sperm .
See also
Individual evidence
- ↑ a b c Entry on agmatine. In: Römpp Online . Georg Thieme Verlag, accessed on November 11, 2018.
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
- ↑ Kossel, Albrecht (1910): About the agmatine . , in: Zeitschrift für Physiologische Chemie . 66, 257-261.
literature
- Morris, SM: "Arginine: beyond protein", in: Am. J. Clin. Nutr. (2006), 83 (2), 508S-512S; PMID 16470022 HTML .