Benzhydrol

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Structural formula
Structural formula of benzhydrol
General
Surname Benzhydrol
other names
  • Diphenylmethanol
  • Diphenyl carbinol
  • Hydroxydiphenylmethane
  • Benzhydryl alcohol
Molecular formula C 13 H 12 O
Brief description

colorless needles

External identifiers / databases
CAS number 91-01-0
EC number 202-033-8
ECHA InfoCard 100,001,849
PubChem 7037
Wikidata Q418377
properties
Molar mass 184.23 g mol −1
Physical state

firmly

Melting point

65-67 ° C

boiling point

297-298 ° C

solubility
  • very heavy in water (0.5 g l −1 at 20 ° C)
  • soluble in alcohol, ether and chloroform
safety instructions
GHS labeling of hazardous substances
07 - Warning

Caution

H and P phrases H: 315-319-335
P: 273-391-501
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Benzhydrol or Diphenylmethanol (C 6 H 5 ) 2 CHOH is a secondary alcohol .

presentation

The easiest way to prepare benzhydrol is to use the Grignard reaction of phenylmagnesium bromide and benzaldehyde . Benzhydrol may, inter alia, by reduction of benzophenone with zinc dust in an alkaline solution are shown. Sodium borohydride in methanol can also be used here as a reducing agent .

properties

Benzhydrol melts between 65 and 67 ° C and boils between 297 and 298 ° C.

use

It is used as a raw material in the pharmaceutical industry, especially for antihistamines .

Individual evidence

  1. ↑ a b c Entry on diphenylmethanol. In: Römpp Online . Georg Thieme Verlag, accessed on May 25, 2014.
  2. ↑ a b data sheet diphenylmethanol 99% from Sigma-Aldrich , accessed on December 20, 2013 ( PDF ).
  3. ↑ a b c Entry on benzhydryl alcohol in the GESTIS substance database of the IFA , accessed on April 5, 2018 (JavaScript required)