Chaitan Khosla
Chaitan Khosla (born August 14, 1964 in Pune ) is an Indian-born chemical engineer at Stanford University .
Khosla earned a bachelor's degree from the Indian Institute of Technology in 1985 and a Ph.D. at the California Institute of Technology . He worked as a postdoctoral fellow at the John Innes Center in the UK . He is professor of chemical engineering, chemistry and biochemistry at Stanford University .
Khosla was able to contribute significantly to the elucidation of the biocatalysis of polyketides , which opened up new ways for the development of pharmaceuticals. In 1995 he founded Kosan Biosciences for commercial exploitation of this knowledge. The company was bought by Bristol-Myers Squibb in 2008 .
In 2002, under the impression that his wife and son had celiac disease, he founded the Celiac Sprue Research Foundation to develop drugs against this disease - initially independently of support from the pharmaceutical industry . Together with his student Lu Shan, Khosla developed a peptidase to inactivate a short but particularly toxic peptide sequence of gluten as a damaging agent. Alvine Pharmaceuticals , founded by Khosla, develops medicines for celiac disease. One approach is to take orally a combination of enzymes to inactivate gluten.
Awards (selection)
- 1999 Alan T. Waterman Award from the National Science Foundation
- 1999 Eli Lilly Award in Biological Chemistry from the Biochemistry Section of the American Chemical Society
- 2000 American Chemical Society Award in Pure Chemistry from the American Chemical Society
- 2006 Fellow of the American Association for the Advancement of Science
- 2007 member of the American Academy of Arts and Sciences
- 2009 member of the National Academy of Engineering
- 2018 Prelog medal and lecture
- 2020 member of the National Academy of Sciences
Web links
- Chaitan Khosla and Khosla Lab at Stanford University (stanford.edu)
Individual evidence
- ↑ Chaitan Khosla: Harnessing the Biosynthetic Potential of Modular Polyketide Synthases. In: Chemical Reviews. 97, 1997, p. 2577, doi: 10.1021 / cr960027u .
- ↑ Guided By Gandalf. In: outlookindia.com. July 12, 2002. Retrieved July 9, 2017 .
- ↑ Professor Chaitan Khosla , Stanford University ( Memento from June 26, 2012 in the Internet Archive )
- ↑ 18 Indian Minds Who Are Doing Cutting Edge Work - Forbes India. In: forbesindia.com. March 3, 2012, accessed July 9, 2017 .
- ^ Stanford researcher to find cure for widespread Celiac disease. In: eurekalert.org. September 26, 2002, accessed July 9, 2017 .
- ↑ Jonathan Gass, Michael T. Bethune, Matthew Siegel, Andrew Spencer, Chaitan Khosla: Combination Enzyme Therapy for Gastric Digestion of Dietary Gluten in Patients With Celiac Sprue. In: Gastroenterology. 133, 2007, pp. 472-480, doi: 10.1053 / j.gastro.2007.05.028 .
- ^ National Science Foundation Alan T. Waterman Award. In: nsf.gov. April 18, 2017, accessed April 3, 2018 .
- ↑ Eli Lilly Award in Biological Chemistry (PDF, 49 kB) at divbiolchem.org; Retrieved July 9, 2017.
- ^ ACS Award in Pure Chemistry. In: acs.org. Retrieved July 9, 2017 .
- ↑ Book of Members 1780 – present, Chapter K. (PDF; 670 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved April 3, 2018 .
- ↑ Dr. Chaitan Khosla. In: nae.edu. Retrieved July 9, 2017 .
| personal data | |
|---|---|
| SURNAME | Khosla, Chaitan |
| BRIEF DESCRIPTION | Indian-born chemical engineer |
| DATE OF BIRTH | August 14, 1964 |
| PLACE OF BIRTH | Pune |