Cystathionine

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Structural formula
Crystal structure Structural formula of L-Cystathionine
General
Surname Cystathionine
other names

( R ) - S - (2-Amino-2-carboxyethyl) - L -homocysteine

Molecular formula C 7 H 14 N 2 O 4 S
Brief description

white solid

External identifiers / databases
CAS number
  • 56-88-2 ( L )
  • 535-34-2 ( D , L )
  • 2998-83-6 ( D )
EC number 200-295-8
ECHA InfoCard 100,000,269
PubChem 439258
ChemSpider 16735760
Wikidata Q28529685
properties
Molar mass 222.26 g mol −1
Physical state

firmly

Melting point

> 300 ° C

safety instructions
GHS labeling of hazardous substances
no GHS pictograms
H and P phrases H: no H-phrases
P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Cystathionine is a non-proteinogenic amino acid that occurs in the biosynthesis of cysteine . Cystathionine is generated from homocysteine and serine by cystathionine-β-synthase . Due to the cystathionine γ-lyase , cystathionine can be hydrolyzed to yield cysteine and α-ketobutyrate formed.

Cystathionine is an amino acid with 2 stereocenters .

As Cystathioninurie which is an autosomal recessive hereditary disease described, in which there is accumulation of cystathionine, which via the urine is excreted.

Individual evidence

  1. a b c d e data sheet L-Cystathionine, ≥98% (TLC) from Sigma-Aldrich , accessed on January 24, 2020 ( PDF ).
  2. Entry on cysteine in Flexikon , a wiki of the DocCheck company , accessed on January 23, 2020.
  3. Cystathioninuria. In: Spectrum Lexicon Nutrition. Retrieved January 23, 2020 .