Elaine A. Ostrander

from Wikipedia, the free encyclopedia
Elaine A. Ostrander

Elaine A. Ostrander (* approx. 1958) is an American geneticist at the National Human Genome Research Institute , part of the National Institutes of Health . Here she heads the Department of Cancer Genetics and Comparative Genomics .

Ostrander acquired in 1987 with the thesis Characterization of psoralen-DNA photoadducts at the nucleotide lievel in pBR322 and SV40 at the Oregon Health & Science University a Ph.D. and worked as a postdoctoral fellow with James Wang at Harvard University . The next stages in her scientific career were the University of California, Berkeley and the Lawrence Berkeley National Laboratory (both in Berkeley , California ), where she was one of the founders of the canine genome project , a project to fully record the genome of dogs (comparable to the Human genome project in humans). Ostrander then worked for twelve years at the Fred Hutchinson Cancer Research Center and the University of Washington (both in Seattle , Washington ), where she was most recently Head of the Department of Genetics, before moving to the National Human Genome Research Institute in Bethesda , Maryland in 2004 . changed.

Elaine Ostrander is concerned with the systematic recording of genetic differences between individual dog breeds , in particular with those genes that are responsible for the shape and size of dogs. She was able to show that the function of numerous genes is significantly more complex than previously assumed. By analyzing diseases that are particularly common in certain dog breeds, she was able to identify genes that are responsible for diseases such as retinitis pigmentosa , epilepsy , renal cell carcinoma , sarcomas or squamous cell carcinoma and that have equivalents in the human genome that are also associated with these diseases are. Other work by Ostrander deals with genetic factors of prostate cancer in humans, a cancer for which there is no suitable animal model .

In 2012 Ostrander was elected to the American Association for the Advancement of Science and in 2019 to the National Academy of Sciences . In 2013 she received the Genetics Society of America Medal , and in 2019 an honorary doctorate from the University of Rennes 1 .

Elaine Ostrander is married and has one birth and one adopted child. Her brother Gary Ostrander is a marine biologist .

literature

Web links

Individual evidence

  1. ↑ Ostrander, Elaine. In: aaas.org. February 24, 2017, accessed March 26, 2018 .
  2. ↑ J. Schimenti, M. Halpern: The 2013 Genetics Society of America Medal: Elaine A. Ostrander. In: Genetics. 194, 2013, p. 5, doi: 10.1534 / genetics.113.150672 .
  3. ↑ Elaine A. Ostrander and Mark G. Humphrey distingués Docteurs Honoris Causa. In: univ-rennes1.fr. April 30, 2019, accessed August 12, 2019 (French).
  4. ^ Gary Ostrander, Elaine Ostrander: Q & A. In: Current Biology. 15, 2005, p. R151, doi: 10.1016 / j.cub.2005.02.035 .
personal data
SURNAME Ostrander, Elaine A.
BRIEF DESCRIPTION American geneticist
DATE OF BIRTH 20th century