Fluxapyroxad

Structural formula
General
Surname	Fluxapyroxad
other names	3- (Difluoromethyl) -1-methyl- N - (3 ', 4', 5'-trifluorobiphenyl-2-yl) pyrazole-4-carboxamide
Molecular formula	C 18 H 12 F 5 N 3 O
Brief description	beige solid
External identifiers / databases
EC number	620-041-3
ECHA InfoCard	100.107.372
PubChem	16095400
ChemSpider	17253690
Wikidata	Q15632875
properties
Molar mass	381.30 g mol −1
Physical state	firmly
Melting point	157 ° C
boiling point	Decomposes at 229 ° C
Vapor pressure	2.7 10 −9 Pa (20 ° C)
solubility	almost insoluble in water (3.88 mg l −1 at 20 ° C); soluble in acetone , dichloromethane , ethyl acetate and acetonitrile ;
safety instructions
H and P phrases	H: 351-410
	P: 273-281-501
Toxicological data	> 2000 mg kg −1 ( LD 50 , rat , oral ) ; > 2000 mg kg −1 ( LD 50 , rat , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Fluxapyroxad is a chemical compound from the group of anilides and pyrazoles .

properties

Fluxapyroxad is a white powder as a pure substance and beige as a technical product, which is practically insoluble in water. It is stable to photolysis in aqueous solution and hydrolysis at pH values of 4, 5, 7 and 9.

use

Fluxapyroxad is used as a fungicide . The effect is based on the inhibition of succinate dehydrogenase in complex II of the mitochondrial respiratory chain.

Admission

Fluxapyroxad was developed by BASF and approved for the first time in the USA in 2012.

The EU Commission approved the use of the active ingredient in plant protection products, fluxapyroxad, with effect from January 1, 2013.

In a number of EU countries, including Germany and Austria, as well as Switzerland, plant protection products with this active ingredient are approved against various fungal diseases in cereals.

Residues in food

In Switzerland, strawberries , edible flowers , fresh herbs as well as lettuce and other types of lettuce (with the exception of endive) have a relatively high maximum residue level of 4 milligrams of fluxapyroxad per kilogram.

literature

EFSA: Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F). In: EFSA Journal. 10, 2012, p. 2522, doi : 10.2903 / j.efsa.2012.2522 .

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h Data sheet Fluxapyroxad from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).
↑ ^a ^b ^c ^d BVL: Fluxapyroxad
↑ ^a ^b FAO: Fluxapyroxad (PDF; 6.3 MB)
↑ EPA: Pesticide Fact Sheet - Fluxapyroxad (PDF; 595 kB)
↑ Implementing Regulation (EU) No. 589/2012 of the Commission of July 4, 2012 on the approval of the active substance fluxapyroxad (PDF) in accordance with Regulation (EC) No. 1107/2009 of the European Parliament and of the Council on the placing of plant protection products on the market and amending it of the Annex of the Commission Implementing Regulation (EU) No. 540/2011.
↑ Directorate-General for Health and Food Safety of the European Commission: Entry on Fluxapyroxad in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; Retrieved February 20, 2016.
↑ Ordinance of the EDI on the maximum levels for pesticide residues in or on products of plant and animal origin. In: admin.ch . Retrieved February 6, 2020 .

[Sigma-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h Data sheet Fluxapyroxad from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).

[BVL-2] BVL: Fluxapyroxad

[FAO-3] FAO: Fluxapyroxad (PDF; 6.3 MB)

[EPA-4] EPA: Pesticide Fact Sheet - Fluxapyroxad (PDF; 595 kB)

[5] Implementing Regulation (EU) No. 589/2012 of the Commission of July 4, 2012 on the approval of the active substance fluxapyroxad (PDF) in accordance with Regulation (EC) No. 1107/2009 of the European Parliament and of the Council on the placing of plant protection products on the market and amending it of the Annex of the Commission Implementing Regulation (EU) No. 540/2011.

[PSM-6] Directorate-General for Health and Food Safety of the European Commission: Entry on Fluxapyroxad in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; Retrieved February 20, 2016.

[7] Ordinance of the EDI on the maximum levels for pesticide residues in or on products of plant and animal origin. In: admin.ch . Retrieved February 6, 2020 .