Hans Robert Schöler

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Hans Robert Schöler (born January 30, 1953 in Toronto , Canada ) is a molecular biologist and stem cell researcher. He is director at the Max Planck Institute for Molecular Biomedicine in Münster.

Live and act

Hans Schöler came to Germany in 1960 and grew up in Paderborn , Munich and Heidelberg . After studying biology at Heidelberg University , Schöler conducted research at the Center for Molecular Biology Heidelberg (ZMBH). The associated results led to his doctorate at Heidelberg University in 1985 .

After working as a research group leader for Boehringer Mannheim at the Tutzing Research Center and as a research assistant at the Max Planck Institute for Biophysical Chemistry in Göttingen , Schöler took over the leadership of a research group at the European Molecular Biology Laboratory ( EMBL ) in Heidelberg in 1991 . During his stay in Göttingen, he discovered the most important stem cell gene Oct-4 , which plays an important role in the reprogramming of stem cells (Nobel Prize for Physiology 2012, S. Yamanaka ). In 1994 he completed his habilitation at the Biological Faculty of the Ruprecht-Karls-Universität Heidelberg.

In 1999 Hans Schöler left the EMBL to take up the professorship for reproductive physiology at the School of Veterinary Medicine at the University of Pennsylvania , USA. At the same time he was director of the Center of Animal Transgenesis and Germ Cell Research. From 2000 to 2004 he held the Marion Dilley and David George Jones Chair in Reproductive Medicine.

Since 2004, Hans Schöler has been Director of the Cell and Developmental Biology Department at the Max Planck Institute for Molecular Biomedicine , Münster. He is professor of the medical faculty of the Westphalian Wilhelms-Universität Münster and also associate professor at the University of Pennsylvania and the Hannover Medical School .

A developmental biologist team led by Hans Schöler at the Max Planck Institute for Molecular Biomedicine in Münster have published research results in the journal Nature . With the help of a single gene, they have succeeded for the first time in transforming human nerve cells into so-called "all-rounders" that can develop into any cell and thus any type of tissue. Schöler rates the quality of the stem cells obtained in this way as so high that the import of embryonic stem cells can almost be dispensed with in the future .

In 2007 the government of North Rhine-Westphalia was looking for future projects and asked Hans Schöler, who then suggested a "Center for Applied Regenerative Development Technologies" (CARE). In North Rhine-Westphalia, his research project “CARE” was later viewed as “not eligible”, also with reference to the budget situation. The project is now to be realized with Schöler in Munich.

research

His research focuses on the molecular biology of germline cells (pluripotent cells and germ cells); transcriptional regulation of genes in the germ line of mammals, decoding of the molecular process of reprogramming somatic cells after induction with transcription factors, nuclear transfer in oocytes or fusion with pluripotent cells.

His over 250 publications have been cited over 14,000 times. His Hirsch index is 75 (as of July 2017).

Awards and memberships

Web links

Individual evidence

  1. ^ Hans R. Schöler, Siegfried Ruppert, Noriaki Suzuki, Kamal Chowdhury, Peter Gruss: New type of POU domain in germ line-specific protein Oct-4 . In: Nature . tape 344 , no. 6265 , March 1990, p. 435-439 , doi : 10.1038 / 344435a0 .
  2. ↑ Michael Hesse: Stem cells now also with morality. In: Kölner Stadtanzeiger . August 28, 2009. Retrieved August 22, 2016 .
  3. ↑ Bernadette Winter: Small cells, big quarrel. In: Deutsche Universitätszeitung (duz). Issue 2/2016, pages 20–23 ( duz.de ).
  4. ^ The Münster stem cell research institute CARE is on hold. In: Deutschlandradio . December 3 and 4, 2013, accessed on August 22, 2016 (MP3; 3.9 MB).
  5. ↑ Ralf Repöhler: Bavarian Millions for Care. In: Westfälische Nachrichten . August 22, 2015. Retrieved August 22, 2016 .
  6. ^ Scopus - Author details (Schöler, Hans Robert). Retrieved July 10, 2017 .
  7. ↑ Member entry by Prof. Dr. Hans Schöler (with picture) at the German Academy of Sciences Leopoldina , accessed on July 20, 2016.
  8. ↑ New members of the Berlin-Brandenburg Academy of Sciences , press release, in: Informationsdienst Wissenschaft from November 26, 2010, accessed on December 10, 2010
  9. ^ Max Delbrück Medal for Stem Cell Researcher Professor Hans Schöler at mdc-berlin.de; Retrieved October 23, 2011
personal data
SURNAME Schöler, Hans Robert
ALTERNATIVE NAMES Schöler, Hans R.
BRIEF DESCRIPTION German molecular biologist and stem cell researcher
DATE OF BIRTH January 30, 1953
PLACE OF BIRTH Toronto