Harold M. Weintraub

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Harold Martin "Hal" Weintraub (born June 2, 1945 in Newark , New Jersey , † March 28, 1995 in Seattle , Washington ) was an American geneticist . He was able to contribute significantly to the understanding of how gene expression leads to cell differentiation . In particular, he investigated the activation of the globin genes and the structure, function and importance of the transcription factor MyoD .

Weintraub earned a bachelor's degree in biology from Harvard University in 1967 and a Ph.D. from the Pennsylvania School of Medicine in 1971. and in 1973 an MD there as a degree in medicine. As a postdoctoral fellow , he worked with Sydney Brenner and Francis Crick on the Medical Research Council . He was then Assistant Professor of Biochemistry at Princeton University , before moving to the Fred Hutchinson Cancer Research Center in 1978 and as Professor of Genetics at the University of Washington (both in Seattle ), where he remained until his death. From 1990 to 1995 he also conducted research for the Howard Hughes Medical Institute (HHMI).

He has co-edited the following scientific journals : Journal of Biological Chemistry , Molecular and Cellular Biology , Cell and Journal of Cell Biology .

Weintraub received the Eli Lilly Award in Biological Chemistry in 1982 , the Richard Lounsbery Award (For elucidating a molecular mechanism by which a single regulatory gene can lead to a program of cell differentiation.) In 1991 and the Pasarow Award for cancer research in 1992 (for 1991). In 1986 he was elected a member of the National Academy of Sciences and in 1988 a member of the American Academy of Arts and Sciences .

Weintraub was married and had two sons. He died of complications from a brain tumor .

The Fred Hutchinson Cancer Research Center has presented a Weintraub Graduate Student Award since 2000 .

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literature

Individual evidence

  1. Harold M. Weintraub, MD, PhD -. In: hhmi.org. Retrieved September 18, 2017 (English).
  2. ^ Eli Lilly Award in Biological Chemistry - The Eli Lilly Award (PDF; 46 kB), winner since 1935, accessed on September 18, 2017.
  3. ^ Richard Lounsbery Award. In: nasonline.org. Retrieved September 18, 2017 .
  4. Harold Weintraub. In: nasonline.org. Retrieved September 18, 2017 .
  5. Book of Members 1780 – present, Chapter W. (PDF; 852 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved September 18, 2017 (English).
  6. ^ Weintraub Graduate Student Award. In: fredhutch.org. Retrieved September 18, 2017 .