Hepacivirus
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Hepacivirus | ||||||||||||||||
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Hepacivirus is a genus of single-stranded RNA viruses in the Flaviviridae family . The most important species is Hepacivirus C with the hepatitis C virus (HCV) discovered in 1989 , for which humans are the only known natural host and which can cause hepatitis C, hepatocellular carcinoma as well as malignant lymphoma .
The GB virus B (GBV-B), discovered in 1995, is able to infect New World monkeys , especially marmosets of the tamarine (Sanguini) tribe . Like HCV, it is blood-borne and similar to HCV and is associated with viral hepatitis. However, GBV-B has never been detected in wild animals and its natural host is therefore unknown.
Systematics
The viruses of this genus are currently divided into 14 species:
- Genus Hepacivirus
- Species Hepacivirus A
- Canine hepacivirus
- Non-primate hepacivirus
- Equine hepacivirus
- Species Hepacivirus B
- GB Virus B (GBV-B)
- Species Hepacivirus C
- Hepatitis C virus
- Species Hepacivirus D
- Guereza hepacivirus
- Species Hepacivirus E
- Rodent Hepacivirus-339
- Species Hepacivirus F
- Rodent Hepacivirus NLR07-Oct70
- Species Hepacivirus G
- Norway rat hepacivirus 1
- Species Hepacivirus H
- Norway rat hepacivirus 2
- Species Hepacivirus I
- Rodent Hepacivirus SAR-3 / RSA / 2008
- Species Hepacivirus J
- Rodent Hepacivirus RMU10-3382 / GER / 2010
- Species Hepacivirus K
- Asked Hepacivirus PDB-829
- Species Hepacivirus L
- Asked Hepacivirus PDB-112
- Species Hepacivirus M
- Bat Hepacivirus PDB-491.1
- Species Hepacivirus N
- Bovine hepacivirus
- Species Hepacivirus A
- not confirmed by ICTV are according to NCBI u. a.
- Species " Hepacivirus P ", host: human
- Species " Chinese broad-headed pond turtle hepacivirus "
- Species " Chinese softshell turtle hepacivirus "
- Species " Guangxi chinese leopard gecko hepacivirus Guangxi "
- Species " Hainan oriental leaf-toed gecko hepacivirus "
- Species " Western African lungfish hepacivirus "
- Species " Wenling moray eel hepacivirus "
- Species " Nanhai dogfish shark hepacivirus "
- Species " Nanhai ghost shark hepacivirus 1 "
- Species " Nanhai ghost shark hepacivirus 2 "
- Species " Wenling shark virus " (WLSV), attacks the graceful dogfish ( Proscyllium habereri , English graceful catshark )
- Species " Xiamen sepia Stingray hepacivirus " attacks the stingrays Urolophus aurantiacus
- Species " Xiamen guitarfish hepacivirus ", attacks guitar rays (Rhinobatidae)
Individual evidence
- ↑ ICTV Master Species List 2018b.v2 . MSL # 34, March 2019
- ↑ a b c d ICTV Taxonomy history: Yellow fever virus . ICTV, EC 51, Berlin, July 2019; Email ratification March 2020 (MSL # 35)
- ↑ a b c Flaviviridae ( en )
- ↑ a b J. T Stapleton, S Foung, A. S Muerhoff, J Bukh, P Simmonds: The GB viruses: A review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae . In: Journal of General Virology . 92, No. 2, 2010, pp. 233-46. doi : 10.1099 / vir.0.027490-0 . PMID 21084497 . PMC 3081076 (free full text).
- ↑ Viral Zone . ExPASy. Retrieved December 11, 2018.
- ↑ Donald B Smith, Paul Becher, Jens Bukh, Ernest A Gould, Gregor Meyers, Thomas Monath, A. Scott Muerhoff, Alexander Pletnev, Rebecca Rico-Hesse, Jack T Stapleton, Peter Simmonds: Proposed update to the taxonomy of the genera Hepacivirus and Pegivirus within the Flaviviridae family . In: Journal of General Virology . 97, No. 11, 2016, pp. 2894-2907. doi : 10.1099 / jgv.0.000612 . PMID 27692039 . PMC 5770844 (free full text).
- ↑ B. Beames, D. Chavez, RE Lanford: GB virus B as a model for hepatitis C virus . In: ILAR J. , 2001, 42 (2), pp. 152-160, PMID 11406717
- ↑ Unclassified Hepacivirus
- ^ Hepacivirus P (species) NCBI
- ↑ Chinese broad-headed pond turtle hepacivirus (species) NCBI
- ↑ Chinese softshell turtle hepacivirus (species) NCBI
- ↑ chinese leopard gecko hepacivirus (species) NCBI
- ↑ Hainan oriental leaf-toed gecko hepacivirus (species) NCBI
- ↑ Western African lungfish hepacivirus (species) NCBI
- ↑ Wenling moray eel hepacivirus (species) NCBI
- ↑ Nanhai dogfish shark hepacivirus (species) NCBI
- ↑ Nanhai ghost shark hepacivirus 1 (species) NCBI
- ↑ Nanhai ghost shark hepacivirus 2 (species) NCBI
- ↑ Wenling shark virus (species) NCBI
- ↑ Mang Shi, Xian-Dan Lin, Nikos Vasilakis, Jun-Hua Tian, Ci-Xiu Li, Liang-Jun Chen, Gillian Eastwood, Xiu-Nian Diao, Ming-Hui Chen, Xiao Chen, Xin-Cheng Qin, Steven G. Widen, Thomas G Wood, Robert B Tesh, Jianguo Xu, Edward C Holmes, Yong-Zhen Zhang: Divergent Viruses Discovered in Arthropods and Vertebrates Revise the Evolutionary History of the Flaviviridae and Related Viruses . In: Journal of Virology . 90, No. 2, 2016, pp. 659-69. doi : 10.1128 / JVI.02036-15 . PMID 26491167 . PMC 4702705 (free full text).
- ↑ Xiamen sepia Stingray hepacivirus (species) NCBI
- ↑ Xiamen guitarfish hepacivirus (species) NCBI