Jacqueline K. Barton
Jacqueline K. Barton (born May 7, 1952 in New York City ) is an American chemist . She is a professor at Caltech .
Barton graduated from Barnard College with a bachelor's degree ( summa cum laude ) in 1974 and graduated from Columbia University with a PhD in inorganic chemistry in 1978 with Stephen Lippard . As a post-doctoral student , she was at Bell Laboratories and Yale University with Robert Shulman. Then she was a professor at Hunter College , from 1983 at Columbia University and from 1989 at Caltech.
She deals with the chemistry of DNA and showed that this not only stores information in the base sequence, but also has interesting physico-chemical properties, especially with regard to the electron transport along the double strand (DNA mediated charge transfer, DNA CT) and its influence on DNA damage and its repair. The enzymes involved in locating and repairing damage in DNA may use DNA CT. She and her research group use special organometallic complexes to study the structure and dynamics of the DNA double strands .
In her research group, she is also developing electronic chips with which the binding site of proteins (such as transcription factors) and m-RNA on the DNA can be localized via DNA CT . This has applications if they serve as markers for cancer and other diseases.
In 1984 Barton became a research fellow from the Alfred P. Sloan Foundation ( Sloan Research Fellow ). In 1987 she received the Eli Lilly Award in Biological Chemistry . In 1991 she became a MacArthur Fellow , in 1992 with the Garvan Olin Medal and in 1996 with the Paul Karrer Medal . In 2006 she received the Willard Gibbs Medal and in 2010 the National Medal of Science . In 2015 she received the Priestley Medal, the American Chemical Society's highest honor . She was also awarded the American Institute of Chemists Gold Medal in 2015 and the Centenary Prize of the Royal Society of Chemistry in 2016 . For 2019, Barton was awarded the NAS Award in Chemical Sciences . In 1999 she was elected a Fellow of the American Association for the Advancement of Science . Barton is a member of the National Academy of Sciences , the American Academy of Arts and Sciences, and the American Philosophical Society .
Jacqueline Barton is married to Peter Dervan and has one daughter.
Web links
Individual evidence
- ↑ Life data, publications and academic family tree of Jacqueline K. Barton at academictree.org, accessed on January 6, 2018.
- ^ Fellows of the AAAS. American Association for the Advancement of Science, accessed July 17, 2019 .
| personal data | |
|---|---|
| SURNAME | Barton, Jacqueline K. |
| BRIEF DESCRIPTION | American chemist |
| DATE OF BIRTH | May 7, 1952 |
| PLACE OF BIRTH | New York City |