Jean-Louis Mandel
Jean-Louis Mandel (born February 12, 1946 in Strasbourg ) is a French geneticist .
Life
Mandel received his doctorate in medicine from the University of Strasbourg in 1971 . In 1973 he obtained a doctorate in biochemistry from Pierre Chambon with a thesis on RNA polymerases . Mandel worked as a postdoctoral fellow at the Medical Institute of Genetics in Toronto , Canada. From 1975 he was again a research assistant at Chambon. Since 1982, Mandel has headed a research group dedicated to the molecular analysis and diagnosis of certain hereditary diseases . In 1978 he became assistant professor at the University of Strasbourg and in 1995 professor of human molecular genetics . From 2002 to 2006 he was - as successor to the founder Chambon - director of the Institut de génétique et biologie moléculaire et cellulaire de Strasbourg (IGBMC, a joint institution of the Institut national de la santé et de la recherche médicale , INSERM, the Center national de la recherche scientifique , CNRS, and the University of Strasbourg). Mandel has been Professor of Human Genetics at the Collège de France since 2004 .
Act
Mandel's scientific work deals primarily with monogenetic diseases of the nervous system . He identified the genes and their mutations that underlie these diseases, developed tests to diagnose these diseases, and examined their pathophysiological mechanisms using animal and cell models . In particular, Mandel published fundamental work on trinucleotide diseases such as fragile X syndrome , Huntington's chorea , Friedreich's ataxia or spinocerebellar ataxias type 2 and type 7, but also on other genetic disorders such as adrenoleukodystrophy and Coffin-Lowry syndrome , myotubular myopathies or vitamin E deficiency ataxia .
Awards (selection)
- 1993 Corresponding member of the Académie des sciences
- 1994 Richard Lounsbery Award
- 1994 member of the Academia Europaea
- 1999 Louis Jeantet Prize
- 1999 Full member of the Académie des Sciences
- 2001 Zülch Prize
- 2004 Neuronal Plasticity Prize
- 2008 Knight of the Légion d'Honneur
Web links
- CV at the Collège de France (college-de-france.fr)
- Mandel, Jean-Louis at the Institut national de la santé et de la recherche médicale (inserm.fr)
- Jean-Louis Mandel at the University of Strasbourg (usias.fr)
- CV (PDF, 99 kB) at the Académie des sciences (academie-sciences.fr)
Individual evidence
- ↑ a b Jean-Louis Mandel. In: academie-sciences.fr. Retrieved February 20, 2016 (French).
- ^ Richard Lounsbery Award at the National Academy of Sciences (nasonline.org); Retrieved December 27, 2012
- ^ Membership directory: Jean-Louis Mandel. Academia Europaea, accessed September 9, 2017 .
- ↑ The 1999 Louis Jeantet Prize Winners at the Louis Jeantet Foundation (jeantet.ch); Retrieved December 27, 2012
- ^ Zülch Prize at the Max Planck Society (mpg.de); Retrieved December 27, 2012
- ^ Neurosciences. (No longer available online.) In: fondation-ipsen.org. Archived from the original on July 21, 2017 ; accessed on February 6, 2016 .
| personal data | |
|---|---|
| SURNAME | Almond, Jean-Louis |
| ALTERNATIVE NAMES | Almond, Jean Louis |
| BRIEF DESCRIPTION | French geneticist |
| DATE OF BIRTH | February 12, 1946 |
| PLACE OF BIRTH | Strasbourg |