Joseph F. Fraumeni
Joseph Francis Fraumeni Jr. (born April 1, 1933 in Boston ) is an American cancer researcher and epidemiologist at the National Cancer Institute , who is known, among other things, for the description of Li Fraumeni syndrome (together with Frederick P. Li ).
Live and act
Fraumeni earned a bachelor's degree from Harvard College and an MD from Duke University with a medical degree. His time as a junior doctor he graduated from the Johns Hopkins Hospital and the Memorial Sloan-Kettering Cancer Center . In 1962 he moved to the Epidemiology Department of the National Cancer Institute (NCI), a facility of the National Institutes of Health based in Bethesda , Maryland . Apart from additional training at the Harvard School of Public Health , where he obtained a master’s degree in 1965 , Fraumeni stayed at the NCI for over 50 years. Here he was director of the department for cancer epidemiology and genetics until 2012 and most recently worked as head of a research group (Senior Investigator) .
Fraumeni deals with epidemiological studies of populations and families in order to identify environmental or genetic causes of cancer . Using computerized maps of the United States at the county level for cancer mortality , Fraumeni and co-workers were able to discover and study high-risk populations for certain types of cancer. In this way, new insights into risk factors in the area of lifestyle and other environmental conditions could be gained , for example the relationship between smokeless tobacco and oral cancer or between asbestos or arsenic and lung cancer .
Fraumeni examined and defined genetic predispositions for familial cancer cases, including the Li-Fraumeni syndrome (1969) together with Frederick P. Li , or syndromes from malformations and cancer, including the WAGR syndrome (1964) together with Robert W. Miller .
More recent work combines epidemiological and molecular biological approaches to describe the relationships between cancer-promoting genes and environmental conditions with regard to the development of cancer.
Awards (selection)
- 1992 Fellow of the American Association for the Advancement of Science
- 1995 Charles S. Mott Prize
- 2002 member of the National Academy of Sciences
- 2009 AACR Award for Lifetime Achievement in Cancer Research
- 2011 member of the American Academy of Arts and Sciences
literature
- Robert N. Hoover: A Conversation with Joseph F. Fraumeni, Jr. In: Epidemiology . tape 24 , no. 6 , 2013, p. 929 , doi : 10.1097 / EDE.0b013e3182a56987 .
Web links
- Joseph F. Fraumeni, Jr., MD In: dceg.cancer.gov. August 1, 2013, accessed August 20, 2016 .
Individual evidence
- ↑ General Motors Cancer Research Awards Laureates 1979–1998 (PDF; 64 kB) at aacrjournals.org; accessed on August 20, 2016.
- ↑ Joseph Fraumeni. In: nasonline.org. Retrieved August 20, 2016 .
- ^ AACR Award for Lifetime Achievement in Cancer Research Winners ; accessed on August 20, 2016.
- ↑ Book of Members 1780 – present, Chapter F. (PDF; 815 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved September 14, 2019 .
| personal data | |
|---|---|
| SURNAME | Fraumeni, Joseph F. |
| ALTERNATIVE NAMES | Fraumeni, Joseph; Fraumeni, Joseph F. Jr .; Fraumeni, Joseph Francis |
| BRIEF DESCRIPTION | American cancer researcher and epidemiologist |
| DATE OF BIRTH | April 1, 1933 |
| PLACE OF BIRTH | Boston |