Laura L. Kiessling

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Laura Lee Kiessling (* 1960 in Milwaukee , Wisconsin ) is an American biochemist .

Life

Laura L. Kiessling was born in 1960 in Milwaukee as the daughter of William E. and LaVonne V. Kiessling, née Korth . She grew up in Lake Mills , a small town in Wisconsin about 85 km west of Milwaukee . She began studying at the University of Wisconsin – Madison , but after a year moved to the Massachusetts Institute of Technology, where she graduated in 1983 with a Bachelor of Science degree in chemistry. As a doctoral student, she then went to Yale University , where she received her PhD in chemistry in 1989 . As a post-doctoral student , she then spent two years at the California Institute of Technology with Peter Dervan and returned in 1991 to the University of Wisconsin – Madison, where she is now (2014) Professor of Chemistry and Biochemistry.

Laura L. Kiessling is married to Ronald T. Raines , who also professor of chemistry and biochemistry at the University of Wisconsin-Madison and the company they Quintessence Biosciences, Inc. has established. They have a daughter together.

research

The research focus of Laura L. Kiessling's laboratory includes the diverse interactions between proteins and carbohydrates , especially the role of glycoproteins in cell interaction. With the help of Ring Opening Metathesis Polymerization (ROMP), a process for chain polymerization , synthetic carbohydrate derivatives of a defined length and chemical structure are created that bind to membrane proteins and thus block or influence them, whereby the cell interaction through the multivalent binding of the carbohydrate groups of glycoproteins can be simulated and examined.

Laura L. Kiessling also devotes herself to the structure and biosynthesis of the mycobacterial cell walls , which are largely made up of carbohydrates , such as Mycobacterium tuberculosis . The aim is to develop active ingredients that can attach to and inhibit the enzymes involved in the synthesis.

Awards (selection)

Web links

Individual evidence

  1. ↑ George Richard (Ed.): Wisconsin alumnus. Vol. 61, No. 2, 1959, p. 36. Retrieved August 31, 2014.
  2. ^ Obituaries: LaVonne V. "Bonnie" Kiessling. Daily Jefferson County Union, October 6, 2008. Retrieved August 31, 2014.
  3. ↑ a b Laura Kiessling. Chemical Heritage Foundation. Retrieved August 31, 2014.
  4. ↑ Laura Kiessling. ( Memento from September 16, 2016 in the Internet Archive ) Kiessling Lab, University of Wisconsin – Madison.
  5. ↑ Business Board. ( Memento from September 16, 2016 in the Internet Archive ) Quintessence Biosciences, Inc.
  6. ↑ Chemistry to Explore and Exploit Multivalent Protein – Carbohydrate Interactions. ( Memento from September 16, 2016 in the Internet Archive ) Kiessling Lab Research, University of Wisconsin – Madison.
  7. ↑ Carbohydrate Polymer Biosynthesis: A New Target for Anti-Tuberculosis Agents. ( Memento from September 16, 2016 in the Internet Archive ) Kiessling Lab Research, University of Wisconsin – Madison.
  8. ^ Camille Dreyfus Teacher-Scholar Awards Program. ( Memento from September 28, 2014 in the Internet Archive ) Camille and Henry Dreyfus Foundation.
  9. ^ Arthur C. Cope Scholar Awards. ( Memento of June 9, 2015 on the Internet Archive ) American Chemical Society (ACS).
  10. ^ Carbohydrate Research Award for Creativity in Carbohydrate Chemistry. ( Memento of July 3, 2016 in the Internet Archive ) International Carbohydrate Organization.
  11. ^ Book of Members, Chapter K. American Academy of Arts & Sciences, p. 301. Retrieved August 30, 2014.
  12. ↑ Laura L. Kiessling. National Academy of Sciences, Members. Retrieved August 30, 2014.
  13. ^ Professor Laura Kiessling Wins ACS Claude S. Hudson Award. University of Wisconsin-Madison, Department of Chemistry, October 15, 2012. Retrieved September 13, 2014.
  14. ^ Alfred Bader Award in Bioinorganic or Bioorganic Chemistry. American Chemical Society (ACS). Retrieved August 30, 2014.
personal data
SURNAME Kiessling, Laura L.
ALTERNATIVE NAMES Kiessling, Laura Lee
BRIEF DESCRIPTION American biochemist
DATE OF BIRTH 1960
PLACE OF BIRTH Milwaukee , Wisconsin