Leviviridae

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Leviviridae
Ms2capsid surface.png

Bacteriophage MS2 capsid

Systematics
Classification : Viruses
Area : Riboviria
Empire : Orthornavirae
Phylum : Lenarviricota
Class : Allassoviricetes
Order : Levivirales
Family : Leviviridae
Taxonomic characteristics
Genome : (+) ssRNA linear
Baltimore : Group 4
Symmetry : icosahedral
Scientific name
Leviviridae
Left
NCBI  Taxonomy: 11989
ViralZone ( ExPASy , SIB): 163

The Leviviridae are a family of viruses that act as bacteriophages to attack various bacteria including Enterobacteria , Caulobacter , Pseudomonas, and Acinetobacter . The taxonomy of the International Committee on Taxonomy of Viruses (ICTV) as of November 2018 recognizes two genera , each with two species .

They are small RNA viruses with a linear, single-stranded RNA - genome of positive polarity , which encode only four proteins . All phages in this family need bacterial pili to bind to and infect the host cell (bacterial cell).

Systematics

With ICTV as of November 2018, the family has two genera, each with two officially recognized species (species):

  • Family Leviviridae

construction

The virus particles (virions) of the Leviviridae are not enveloped with icosahedral or spherical geometries and with a triangulation number (symmetry) T = 3 . The diameter is about 26 nm. The genome is linear and not segmented with a size of about 4000 nucleotide bases . It codes for 4 proteins .

Mode of action

After entering the host cell, replication takes place in the model for RNA viruses of positive polarity. The virus emerges from the host cell through bacterial lysis .

The four encoded proteins are the coat protein (for the capsid ), the replicase , the maturation protein (A protein) and the lysis protein, the associated genes are called cp , rep , mat and lys .

Individual evidence

  1. ↑ ICTV Master Species List 2018b v1 MSL # 34, Feb. 2019
  2. ↑ a b c d ICTV: ICTV Master Species List 2019.v1 , New MSL including all taxa updates since the 2018b release, March 2020 (MSL # 35)
  3. ↑ a b c Viral Zone . ExPASy. Retrieved December 19, 2018.
  4. ↑ ICTV: ICTV Master Species List 2018a v1 . Retrieved December 19, 2018.
  5. ↑ a b JP Bollback, JP Huelsenbeck: Phylogeny, genome evolution, and host specificity of single-stranded RNA bacteriophage (family Leviviridae). . In: Journal of Molecular Evolution . 52, No. 2, February 2001, pp. 117-28. doi : 10.1007 / s002390010140 . PMID 11231891 .
  6. ↑ SIB: Allolevivirus , on: ViralZone
  7. ↑ SIB: Levivirus , on: ViralZone

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