Lithium chloroacetate

Structural formula
General
Surname	Lithium chloroacetate
Molecular formula	C 2 H 2 ClLiO 2
Brief description	white solid
External identifiers / databases
CAS number 19326-51-3 PubChem 23695591 ChemSpider 13875802 Wikidata Q15719293
properties
Molar mass	100.43 g cm −3
Physical state	firmly
safety instructions
GHS hazard labeling no classification available
Thermodynamic properties
ΔH f 0	−815.95 kJ mol −1 .
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Lithium chloroacetate is the lithium salt of chloroacetic acid with the empirical formula C ₂ H ₂ ClO ₂ Li.

Extraction and presentation

Lithium chloroacetate can be prepared from lithium hydroxide and chloroacetic acid in methanol or ethanol by the salt formation reaction .

${\displaystyle \mathrm {LiOH+CH_{2}ClCOOH\longrightarrow CH_{2}ClCOOLi+H_{2}O} }$

A synthesis from lithium hydride and chloroacetic acid in THF has also been described.

properties

Lithium chloroacetate crystallizes in the monoclinic crystal system in the space group P 2 ₁ / c (space group no. 14) with the lattice parameters a  = 938.8  pm , b  = 484.5 pm, c  = 901.2 pm and β  = 94.33 ° . In the unit cell contains four formula units . The crystals are isomorphic to lithium bromoacetate and lithium iodoacetate .

In contrast to many other halogen acetates of the alkali metals , lithium chloroacetate does not undergo any polymerization reaction to form polyhydroxyacetic acid in the solid state .

Lithium chloracetate decomposes into lithium chloride , carbon dioxide and water when heated in air .

Individual evidence

1. ↑ ^{a b} Patent application CA1339748 : Glycolate Ester Peracid Precursors. Applied on October 28, 1987 , published on March 17, 1998 , Applicant: Clorox , Inventor: RA Fong, SN Lewis, RJ Wiersema, AG Zielske. ‌
2. ↑ ^{a b} E. Homberger-Zizzari: Porphobilinogene Synthase (PBGS) d'Escherichia Coli: Etudes cinetiques et rayons X, Deux outils permettant la caracterisation du site actif et la determination du mecanisme enzymatique. Dissertation 2002. Université de Friborg ( full text ).
3. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
4. ↑ ^{a b} O. Herzberg: Investigation of organic solid-state reactions using the example of substitution and polycondensation reactions . Hamburg 2000, DNB  960245774 , urn : nbn: de: gbv: 18-2380 (dissertation, University of Hamburg).
5. ↑ M. Epple, O. Herzberg: Polyglycolide with controlled porosity: an improved biomaterial . In: Journal of Materials Chemistry . tape 7 , no. 6 , 1997, pp. 1037-1042 , doi : 10.1039 / A700275K .
6. ↑ ^{a b c} H. Ehrenberg, B. Hasse, K. Schwarz, M. Epple: Structure determination of lithium chloroacetate, lithium bromoacetate and lithium iodoacetate by powder diffraction . In: Acta Crystallographica Section B Structural Science . tape 55 , no. 4 , 1999, p. 517-524 , doi : 10.1107 / S0108768199003614 ( PDF ).