Mevinphos

Structural formula
	Mixture of approx. 60% cis isomer (top) and 40% trans isomer (bottom)
General
Surname	Mevinphos
other names	Phosdrine; O - (2-methoxycarbonyl-1-methylvinyl) - O , O -dimethyl phosphate; (2-methoxycarbamoyl-1-methylvinyl) dimethyl phosphate;
Molecular formula	C 7 H 13 O 6 P
Brief description	light yellow to orange liquid with a faint odor
External identifiers / databases
ECHA InfoCard	100.029.177
PubChem	5355863
Wikidata	Q18479302
properties
Molar mass	224.15 g mol −1
Physical state	liquid
density	1.25 g cm −3
Melting point	21 ° C ( cis isomer); 6.9 ° C ( trans isomer);
boiling point	99-103 ° C (0.4 mbar)
Vapor pressure	0.037 mbar (20 ° C)
solubility	miscible with water; soluble in acetone and benzene;
safety instructions
H and P phrases	H: 300 + 310-331-410
	P: 261-264-273-280-301 + 310-302 + 350
MAK	Switzerland: 0.01 ml m −3 or 0.1 mg m −3
Toxicological data	3 mg kg −1 ( LD 50 , rat , oral ) ; 4.7 mg kg −1 ( LD 50 , rabbit , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Mevinphos is an active ingredient for plant protection products, it is a chemical compound from the group of organophosphates or phosphoric acid esters .

Extraction and presentation

Mevinphos can be obtained by the Perkow reaction of trimethyl phosphite with methyl 2-chloroacetoacetate .

properties

Mevinphos is a colorless in its pure form, as a technical product light yellow to orange, very difficult to ignite, liquid with a weak odor, which is miscible with water. The technical product consists of approx. 60% of the cis - isomer . It is largely stable in a neutral and acidic medium, but it hydrolyzes rapidly under alkaline conditions.

use

Mevinphos is used as an insecticide and acaricide . It works by inhibiting cholinesterase .

Admission

In 2002 the substance was not included in the list of plant protection active ingredients approved in the European Union . No plant protection products containing this active ingredient are permitted in the EU or Switzerland .

Web links

Joint Meeting on Pesticide Residues (JMPR), Monograph for Mevinphos

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m Entry on Mevinphos in the GESTIS substance database of the IFA , accessed on January 8, 2018(JavaScript required) .
↑ ^a ^b ^c ^d M. Bahadir, H. Parlar, Michael Spiteller: Springer Umweltlexikon . Springer, 2000, ISBN 978-3-540-63561-1 , pp. 767 ( limited preview in Google Book search).
↑ entry to Mevinphos at Extoxnet, accessed on 21 January 2018th
↑ Entry on Mevinphos in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Swiss Accident Insurance Fund (Suva): Limit values - current MAK and BAT values (search for 7786-34-7 or Mevinphos ), accessed on March 4, 2020.
↑ Jie Jack Li, EJ Corey: Name reactions for functional group transformations . John Wiley & Sons, 2007, ISBN 978-0-471-74868-7 , pp. 381 ( limited preview in Google Book Search).
↑ General Directorate Health and Food Safety of the European Commission: Entry on Mevinphos in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 26, 2016.

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m Entry on Mevinphos in the GESTIS substance database of the IFA , accessed on January 8, 2018(JavaScript required) .

[Springer-2] M. Bahadir, H. Parlar, Michael Spiteller: Springer Umweltlexikon . Springer, 2000, ISBN 978-3-540-63561-1 , pp. 767 ( limited preview in Google Book search).

[3] try to Mevinphos at Extoxnet, accessed on 21 January 2018th

[CLP_100.029.177-4] Entry on Mevinphos in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[5] Swiss Accident Insurance Fund (Suva): Limit values - current MAK and BAT values (search for 7786-34-7 or Mevinphos ), accessed on March 4, 2020.

[buch-6] Jie Jack Li, EJ Corey: Name reactions for functional group transformations . John Wiley & Sons, 2007, ISBN 978-0-471-74868-7 , pp. 381 ( limited preview in Google Book Search).

[7] General Directorate Health and Food Safety of the European Commission: Entry on Mevinphos in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 26, 2016.