Michael Hecker

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Michael Hecker (born  July 9, 1946 in Annaberg ) is a German micro and molecular biologist . He has been a professor at the University of Greifswald since 1986 , his main research areas being the physiology of microorganisms and genome research .

Academic and professional career

Michael Hecker put 1965 in Zwickau , the High School , and then graduated to 1970 to study biology at the University of Greifswald , where he with a thesis in 1973 metabolism of nucleic acids and proteins in Agrostemma githago also received his doctorate . In 1977 he also received his habilitation at the University of Greifswald . From 1986 he was Professor of Molecular Biology in Greifswald, and in 1990 he was appointed C4 Professor and Director of the Institute for Microbiology and Molecular Biology, which Hecker headed until 2013. From 1990 to 1994 Hecker was Dean of the Faculty of Mathematics and Natural Sciences.

Scientific contribution

Michael Hecker deals with the physiology of bacteria. To this end, he and his colleagues have set up a center for proteomics of microorganisms in Greifswald . The Greifswald microbiologists are able to identify the proteome , i. H. to record and quantify the entirety of the proteins of model bacteria. Since proteins are the actual tools of life, one can obtain comprehensive and new knowledge of its physiology from the perspective of the protein inventory of a cell. Main areas of work, which are all based on physiological proteome analysis, are the analysis of the stress and hunger response of bacteria as well as the physiology and virulence of pathogenic bacteria.

Membership in international organizations

Functions in scientific societies and committees (selection)

  • 1993–1996 expert reviewer for microbiology by the German Research Foundation (DFG)
  • 1995–2001 President and Vice President of the VAAM ( Microbiological Society )
  • Member of the editorial boards of various journals and senior editor of the journals Proteomics and Proteomics - Clinical Applications

Awards

  • 2006 Research / Technology Invention Award, Henkel KGaA
  • 2012 Research Prize from the Doctor Robert Pfleger Foundation for basic medical research
  • 2013 Senior Research Award from the Greifswald University Club
  • 2013 North German Science Prize
  • 2013 Entry in the Golden Book of the Hanseatic City of Greifswald
  • 2017 honorary membership of the VAAM

Project coordination, membership in joint projects (selection)

Coordinator of numerous third-party funded projects, funded by the DFG, the BMBF, the EU, industry or the state of Mecklenburg-Western Pomerania.

Works

Around 400 original papers in scientific journals ( PubMed ).

  • with W. Babel: Physiology of microorganisms: The cell, its environment and the mechanisms of adaptation. VEB Gustav Fischer Verlag, Jena / Stuttgart 1988.
  • with S. Müllner (Ed.): Proteomics of Microorganisms . Springer, 2003.
  • with I. Humphery-Smith (Ed.): Microbial Proteomics. Functional Biology of Whole Organisms . Wiley, USA 2006.
  • with P. Jungblut (Ed.): Proteomics of Microbial Pathogens . Wiley-VCH, 2007.
  • with J. Hacker (Ed.): What is life? Scientific publishing company, Stuttgart 2012.

Web links

Individual evidence

  1. M. Hecker, J. Pané-Farré, U. Völker: SigB-dependent general stress response in Bacillus subtilis and related gram-positive bacteria. In: Annu. Rev. Microbiol. 61 (2007), pp. 215-236.
  2. Jump up ↑ Dörte Becher, Knut Büttner, Martin Moche, Bernd Heßling, Michael Hecker: From the genome sequence to the protein inventory of Bacillus subtilis. In: Proteomics. 11 (2011), pp. 2971-2980.
  3. A. Otto, J. Bernhardt, H. Meyer, M. Schaffer, FA Herbst, J. Siebourg, U. Mäder, M. Lalk, M. Hecker, D. Becher: Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis. In: Nat Commun. 1, 2010, p. 137. doi: 10.1038 / ncomms1137 .
  4. M. Hecker, D. Becher, S. Fuchs, S. Engelmann: A proteomic view of cell physiology and virulence of Staphylococcus aureus. In: Int J Med Microbiol. 300 (2-3), 2010 Feb, pp. 76-87. Review.
  5. F. Götz, J. Hacker, M. Hecker: Pathophysiology of staphylococci in the post-genomic era. In: Int. J. Med. Microbiol. 300 (2-3), 2010, pp. 75-204.
  6. Member entry by Prof. Dr. Michael Hecker (with picture and CV) at the German Academy of Sciences Leopoldina , accessed on July 12, 2016.
  7. American Academy of Microbiology
  8. ^ IUMS
  9. ^ Research / Technology Invention Award, Henkel 2006
  10. Research Award of the Doctor Robert Pfleger Foundation 2012
  11. ^ Senior Research Award from the Greifswald University Club
  12. North German Science Award ( Memento of the original from July 2, 2015 in the Internet Archive ) Info: The archive link has been inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2Template: Webachiv / IABot / www.uni-greifswald.de
  13. Entry in the Golden Book of the Hanseatic City of Greifswald
  14. ^ Greifswald - Honor for Greifswald's most famous microbiologist - OZ - Ostsee-Zeitung. In: ostsee-zeitung.de. March 20, 2017. Retrieved May 20, 2017 .