Monika Brunner-Weinzierl

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Monika C. Brunner-Weinzierl

Monika Brunner-Weinzierl (* 1966 in Landshut ) is a German immunologist and biologist . Since 2016 she has been the first Vice Rector for Research, Technology and Equal Opportunities at Otto von Guericke University Magdeburg .

Life

Monika C. Brunner-Weinzierl studied biology and computer science at the Free University of Berlin and the University of Western Australia (UWA) in Perth from 1985 to 1991 . In 1995 she did her doctorate on the subject of "T-cell cytokine responses associated with a protective major histocompatibility complex class II allele" at the German Rheuma Research Center (DRFZ) Berlin at NA Mitchison . As a postdoctoral fellow , she worked with Jim Allison , Department of Cancer Research at the University of California, Berkeley . Further research stays in the USA and working group leaders followed, before she was recognized as a specialist immunologist in 2003. In the same year she completed her habilitation. In 2007 she was appointed professor for experimental pediatrics and was entrusted with the management of research and immunodiagnostics at the University Children's Hospital, Otto-von-Guericke University Magdeburg. Since 2016 she has been a member of the rectorate and the first female vice rector for research, technology transfer and equal opportunities. Monika Brunner-Weinzierl is married to Stefan Weinzierl and has two children.

Research services

Ms. Brunner-Weinzierl researches the properties of the defense against infection in small children and the pathogenesis of allergies and autoimmune diseases. Furthermore, she deals with "immune checkpoint" therapies for tumor rejection, as well as the molecular mechanisms of T-cell differentiation. She is head of research at the children's clinic, clinical immunodiagnostics and spokesperson for the research association for perinatal immunology. In 2011, the funding for innovative teaching at the children's clinic went to the work of Ms. Brunner-Weinzierl. The teaching project established there combines old Socrates approaches with the latest technology: questions in the lecture hall should get the best out of the learner. The main point is that the teacher can use questions to track how much the students have understood of the lecture.

Research priorities

Memberships and honors

Memberships

Awards

  • Scholarship holder (in the USA) from the Federal Ministry of Education and Research (BMBF) , awarded by the DKFZ, Heidelberg. Emmy Nöther precursor program : Infection Research, 1995–1997
  • Scholarship holder (domestic) of the BMBF, awarded by the DKFZ, Heidelberg. Emmy Nöther predecessor program: Infection Research, 1997–2000
  • Rahel Hirsch scholarship holder of the Charité HU-Berlin , 2002–2004
  • Prize winner of the Wolfgang Schulze Foundation , awarded by the Rheumaliga, 2003 and 2004
  • Inclusion of the publication Pandiyan et al., 2004, J. Exp. Med. 199: 381 among the 1000 best publications in biology ( Faculty of 1000 ), 2004
  • "Personal research funding for appointment ability" awarded to the best 10% private lecturers at Charité Berlin , 2006
  • Max Hirsch Lecturer SS07 at Charité Berlin, 2007
  • Incorporation of the publication Hoff et al., 2009, J. Immunol. 182: 5342 among the 1000 best publications in medicine ( Faculty of 1000 ), 2009;
  • Award of the publication Rudolph et al., 2011 , J. Immunol. 182: 5342 as a "Research Highlight" by Nature Immunology , 2011

Selected publications

  • Pushpa Pandiyan, Dagmar Gärtner, Osman Soezeri, Andreas Radbruch, Klaus Schulze-Osthoff, Monika C. Brunner-Weinzierl: CD152 (CTLA-4) Determines the Unequal Resistance of Th1 and Th2 Cells against Activation-induced Cell Death by a Mechanism Requiring PI3 Kinase function . In: The Journal of Experimental Medicine . tape 199 , no. 6 . Rockefeller University Press, pp. 831–842 , doi : 10.1084 / jem.20031058 .
  • Holger Lingel, Josef Wissing, Aditya Arra, Denny Schanze, Stefan Lienenklaus, Frank Klawonn, Mandy Pierau, Martin Zenker, Lothar Jänsch, Monika C Brunner-Weinzierl: CTLA-4-mediated posttranslational modifications direct cytotoxic T-lymphocyte differentiation . In: Cell Death and Differentiation . June 23, 2017, doi : 10.1038 / cdd.2017.102 ( nature.com ).
  • Paula Kolar, Karin Knieke, J. Kolja E. Hegel, Dagmar Quandt, Gerd-R. Burmester, Holger Hoff, Monika C. Brunner-Weinzierl: CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice . In: Arthritis & Rheumatism . tape 60 , no. 1 . Wiley Subscription Services, Inc., A Wiley Company, 2009, p. 123–132 , doi : 10.1002 / art.24181 .
  • Dagmar Gärtner, Holger Hoff, Ulrike Gimsa, Gerd-R. Burmester, Monika C. Brunner-Weinzierl: CD25 regulatory T cells determine secondary but not primary remission in EAE: Impact on long-term disease progression . In: Journal of Neuroimmunology . tape 172 , no. 1 , 2006, p. 73-84 , doi : 10.1016 / j.jneuroim 2005.11.003 .
  • Eva Freier, Cora Stefanie Weber, Ulrike Nowottne, Christiane Horn, Katrin Bartels, Sabrina Meyer, York Hildebrandt, Tim Luetkens, Yanran Cao, Caroline Pabst, Julia Muzzulini, Benjamin Schnee, Monika Christine Brunner-Weinzierl, Maurizio Marangolo, Carsten Bokemeyer, Hans -Christian Deter, Djordje Atanackovic: Decrease of CD4 + FOXP3 + T regulatory cells in the peripheral blood of human subjects undergoing a mental stressor . In: Elsevier BV (Ed.): Psychoneuroendocrinology . June 2010, p. 663-673 , doi : 10.1016 / j.psyneuen.2009.10.005 .
  • Ana Stojanovic, Nathalie Fiegler, Monika Brunner-Weinzierl and Adelheid Cerwenka: CTLA-4 Is Expressed by Activated Mouse NK Cells and Inhibits NK Cell IFN-γ Production in Response to Mature Dendritic Cells . In: The American Association of Immunologists (Ed.): The Journal of Immunology . tape 192 , no. 9 , March 31, 2014, p. 4184-4191 , doi : 10.4049 / jimmunol.1302091 .

Web links

Individual evidence

  1. ↑ New management team at the University of Magdeburg starts work. (PDF) November 16, 2016, accessed August 15, 2017 .
  2. ↑ Immune system seeks employment. Volksstimme Magdeburg, May 28, 2015, accessed on August 15, 2017 .
  3. ^ Statement on the further development of university medicine at the Otto von Guericke University Magdeburg. September 7, 2009, accessed August 15, 2017 .
  4. ↑ Magdeburg researchers decipher switches for the uncontrolled multiplication of leukemia T cells. Retrieved August 28, 2017 .
personal data
SURNAME Brunner-Weinzierl, Monika
BRIEF DESCRIPTION German immunologist and biologist
DATE OF BIRTH 1966
PLACE OF BIRTH Landshut