N , N ′ -di- o -tolylguanidine

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Structural formula
Structural formula of N, N′-di-o-tolylguanidine
General
Surname N , N ′ -di- o -tolylguanidine
other names
  • 1,2-bis (2-methylphenyl) guanidine ( IUPAC )
  • 1,3-di- o -tolylguanidine
  • DOTG
  • sym . -di- o -tolylguanidine
Molecular formula C 15 H 17 N 3
Brief description

white to light pink powder with a faint odor

External identifiers / databases
CAS number 97-39-2
EC number 202-577-6
ECHA InfoCard 100.002.344
PubChem 7333
ChemSpider 7056
Wikidata Q426022
properties
Molar mass 239.35 g mol −1
Physical state

firmly

density

1.10 g cm −3

Melting point

179 ° C

solubility
  • practically insoluble in water (70 mg l −1 at 20 ° C)
  • soluble in diethyl ether and chloroform
  • soluble in acetone, ethyl acetate
  • slightly soluble in benzene and ethanol
  • insoluble gasoline and carbon tetrachloride
safety instructions
GHS labeling of hazardous substances
06 - Toxic or very toxic

danger

H and P phrases H: 301-412
P: 273-280-301 + 310-501
Toxicological data

500 mg kg −1 ( LD 50 ,  rat ,  oral )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

N , N ′ -di- o -tolylguanidine is a chemical compound from the group of guanidine derivatives .

Extraction and presentation

N , N '-di- o -tolylguanidine can be obtained from o -toluidine and cyanogen chloride.

properties

N , N ′ -di- o -tolylguanidine is a flammable, white solid that is practically insoluble in water. When heated, it decomposes, releasing nitrogen oxides , carbon monoxide and carbon dioxide .

use

N , N '-di- o -tolylguanidine is used as a vulcanization accelerator and primary titre substance , as well as an intermediate for organic syntheses.

safety instructions

N , N ′ -di- o -tolylguanidine is not itself carcinogenic, but may still contain o -toluidine , which is carcinogenic, due to the manufacturing process . If the content of o- toluidine exceeds 0.1 percent , the mixture must therefore be regarded as carcinogenic.

Related links

Individual evidence

  1. ↑ a b c d e f g h i Entry on N, N′-di-o-tolylguanidine in the GESTIS substance database of the IFA , accessed on January 15, 2020(JavaScript required) .
  2. ↑ Data sheet 1,3-Di-o-tolylguanidine from Sigma-Aldrich , accessed on January 28, 2018 ( PDF ).
  3. ↑ Entry on 1,3-Di-o-tolylguanidine at TCI Europe, accessed on June 27, 2011.
  4. ↑ a b c d Toxicological assessment of 1,3-di-o-tolylguanidine (PDF) from the trade association raw materials and chemical industry (BG RCI), accessed on August 22, 2012.
  5. ↑ GISChem: N, N′-Di-o-tolylguanidin (DOTG) (PDF file; 186 kB), accessed on May 7, 2018