Neurospora crassa
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Hyphae of Neurospora crassa |
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| Shear & BO Dodge |
Neurospora crassa is a red mold from the department of hose mushrooms (Ascomycota).
It is a well-known model organism in biology that is easy to grow. It has a haplontic life cycle that allows easy genetic analysis. Neurospora was chosen as the subject of study by Edward Tatum and George Wells Beadle . In 1958 they received the Nobel Prize for their work . They exposed the mold to ionizing radiation to trigger mutations . They then examined the metabolic pathways for defects in enzyme activities . From their observations, they derived the one-gene-one-enzyme hypothesis , which is only valid to a limited extent today.
In April 2003 the genome of N. crassa was published as sequenced in Nature . It is around 43 megabases and contains around 10,000 genes .
The fungus occurs naturally mainly in the tropical and subtropical regions and predominantly on decaying plant material. Similar to the bacterium Serratia marcescens , it may also thrive on hosts and can discolor them red and thus give the wrong impression of a host miracle .
Systematics
N. crassa serves as a representative for the clade around the taxon of the Nucletmycea .
Web links
- Neurospora Homepage (English)
- Systematic Study of Chaetosphaeria and Lasiosphaeria. In: Website The Field Museum, Chicago, IL, USA . Retrieved March 27, 2013 .
- Mold with jet lag. On: Wissenschaft.de from January 4, 2011
- Video: Life cycle of the red mold Neurospora crassa . Institute for Scientific Film (IWF) 1999, made available by the Technical Information Library (TIB), doi : 10.3203 / IWF / C-1954 .
Individual evidence
- ^ JE Galagan, SE Calvo, KA Borkovich et al .: The genome sequence of the filamentous fungus Neurospora crassa . Nature, no. 422 , 2003, p. 859-868 , doi : 10.1038 / nature01554 ( HTML Online ).
- ↑ US diocese: the supposed blood miracle was just a mold. In: kath.net , December 18, 2015, accessed January 8, 2019; restrictive: Michael O'Loughlin: Utah's 'bleeding host' isn't a miracle, Church says. In: Crux , December 16, 2015, accessed on January 8, 2019: From the original sound of the press release of the Diocese of Salt Lake City cited here , it is clear that it must remain open whether the cause of the discoloration is actually a red mold like Neurospora crassa or not but the Bacterium prodigiosum ( Serratia marcescens ) was.
- ^ SM Adl, AGB Simpson, CE Lane, J. Lukeš, et al .: The Revised Classification of Eukaryotes . Journal of Eukaryotic Microbiology, No. 59 (5) , 2012, p. 429–493 , doi : 10.1111 / j.1550-7408.2012.00644.x ( PDF online ).