Oxybuprocaine
Structural formula | ||||||||||||||||
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General | ||||||||||||||||
Non-proprietary name | Oxybuprocaine | |||||||||||||||
other names |
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Molecular formula | C 17 H 28 N 2 O 3 | |||||||||||||||
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Drug information | ||||||||||||||||
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properties | ||||||||||||||||
Molar mass | 308.42 g · mol -1 | |||||||||||||||
Melting point |
157-160 ° C (monohydrochloride) |
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boiling point |
215–218 ° C (2.7 hPa) |
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solubility |
Monohydrochloride: soluble in water |
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safety instructions | ||||||||||||||||
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Toxicological data | ||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Oxybuprocaine is a locally effective anesthetic that is mainly used in ophthalmology (ophthalmology) and in ear, nose and throat medicine (otolaryngology). It is used in medicines as monohydrochloride . The active ingredient was patented by Wander in 1951 .
It is also used for localized inflammation in the throat and throat , often in combination with tyrothricin .
Trade names
Benoxinat (A), Cebesin (CH), Conjuncain (D), Novain (A), Novesine (D, CH), as well as a generic (CH)
Collu-Blache (CH), Fluoresceine-Oxybuprocaine (CH), Flurekain (A), Mebucaine (CH), Thilorbin (D)
Individual evidence
- ↑ a b c d e Entry on Oxybuprocaine. In: Römpp Online . Georg Thieme Verlag, accessed on July 20, 2019.
- ↑ a b Datasheet Benoxinate hydrochloride from Sigma-Aldrich , accessed on April 16, 2011 ( PDF ).
- ^ Entry on oxybuprocaine in the ChemIDplus database of the United States National Library of Medicine (NLM) .