Philip A. Beachy

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Philip Arden Beachy (born October 25, 1958 in Red Lake , Ontario , Canada ) is an American biochemist , cell and developmental biologist at the Stanford School of Medicine and the Howard Hughes Medical Institute .

Life

Beachy earned a bachelor's degree in science from Goshen College in Goshen , Indiana in 1979 and - after several lectures in chemistry at Indiana University Bloomington - in 1986 from David Hogness at Stanford University in Stanford , California , with a thesis on Molecular biology of homeotic gene function in Drosophila a Ph.D. in biochemistry . As a postdoctoral fellow , Beachy worked with a Sloan Research Fellowship at the Carnegie Institution in Baltimore , Maryland , before becoming Professor of Molecular Biology and Genetics (1988 Assistant Professor , 1993 Associate Professor , 1998 Full Professor) at the Johns Hopkins University School of Medicine in Baltimore. Beachy has also been doing research for the Howard Hughes Medical Institute since 2000 . In 2004 he also received a professorship in oncology at Johns Hopkins University . In 2006 Beachy moved to the Stanford School of Medicine in Stanford , California, where he is now (2012) Professor of Stem Cell Biology and Regenerative Medicine , Developmental Biology and Biochemistry.

Act

Beachy did fundamental work on the hedgehog signaling pathway , which is used to regulate the critical steps in embryonic development in animals. He made the surprising discovery that cholesterol plays an important role in the formation of the hedgehog protein, which resulted in new aspects of the lipid modification of signal proteins. Beachy was able to explain further important steps in this signal transduction .

Awards (selection)

literature

Web links

Individual evidence

  1. ^ NAS Award in Molecular Biology. In: nasonline.org. Retrieved January 13, 2016 .
  2. ^ Philip Beachy. In: nasonline.org. Retrieved May 7, 2019 .
  3. Book of Members 1780 – present, Chapter B. (PDF; 1.2 MB) In: American Academy of Arts and Sciences (amacad.org). Retrieved May 7, 2019 .
  4. ^ March of Dimes Prize in Developmental Biology: Previous Recipients ( Memento from February 13, 2009 in the Internet Archive ) at marchofdimes.com
  5. The 2011 Keio Medical Science Prize Awardees at Keiō University (keio.ac.jp); Retrieved February 18, 2012