Propamocarb

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Structural formula
Structural formula of propamocarbStructural formula of propamocarb hydrochloride
General
Surname Propamocarb
other names
  • O -propyl- N - [3- (dimethylamino) propyl] carbamate
  • Previcur N
Molecular formula C 9 H 20 N 2 O 2
Brief description

colorless, strongly hygroscopic crystals

External identifiers / databases
CAS number 24579-73-5
EC number 607-406-2
ECHA InfoCard 100.109.082
PubChem 32490
Wikidata Q1927058
properties
Molar mass 188.27 g mol −1
Physical state

firmly

density

1.16 g cm −3 ( hydrochloride )

Melting point

45–55 ° C (hydrochloride)

solubility

very light in water (1005 g l −1 at 20 ° C, hydrochloride)

safety instructions
GHS labeling of hazardous substances
07 - Warning

Caution

H and P phrases H: 302
P: no P-phrases
Toxicological data

> 1330 mg kg −1 ( LD 50ratoral , hydrochloride)

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Propamocarb is a chemical compound from the carbamate group and a systemic fungicide introduced by Schering (now Bayer CropScience ) in 1975 . It is mainly used as a hydrochloride.

Extraction and presentation

Propamocarb can be obtained by reacting 3- (dimethylamino) -1-propylamine with propyl chloroformate .

Propamocarb synthesis01.svg

use

Estimated US application rate in 2011

Propamocarb is used as a fungicide to combat fungal diseases, especially phycomycetes such as downy mildew , Pythium and Phytophthora , in strawberry, tobacco and vegetable cultivation as well as in ornamental plants and ornamental trees.

Admission

Propamocarb is approved as an active ingredient in Germany, Austria and Switzerland.

Individual evidence

  1. a b c d e entry on propamocarb hydrochloride. In: Römpp Online . Georg Thieme Verlag, accessed on May 20, 2014.
  2. a b Entry on propamocarb hydrochloride in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on May 20, 2014.
  3. a b Data sheet Propamocarb, PESTANAL at Sigma-Aldrich , accessed on May 19, 2017 ( PDF ).
  4. Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 94 ( limited preview in Google Book search).
  5. Previcur N data sheet
  6. ^ Directorate-General for Health and Food Safety of the European Commission: Entry on Propamocarb in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on February 15, 2016.