Propham

Structural formula
General
Surname	Propham
other names	O -Isopropyl- N -phenylcarbamate
Molecular formula	C 10 H 13 NO 2
Brief description	white solid
External identifiers / databases
CAS number 122-42-9 EC number 204-542-0 ECHA InfoCard 100.004.130 PubChem 24685 ChemSpider 23083 Wikidata Q15975449
properties
Molar mass	179.21 g mol −1
Physical state	firmly
density	1.09 g cm −3
Melting point	90 ° C
solubility	very easily soluble in benzene and ethanol
safety instructions
GHS labeling of hazardous substances Caution H and P phrases H: 302 P: 301 + 312 + 330
Toxicological data	1000 mg kg −1 ( LD 50 ,  rat ,  oral )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Propham is an active ingredient in plant protection and belongs to the carbamate class .

history

Propham was developed by Imperial Chemical Industries (ICI, now Zeneca ).

effect

Propham is a selective herbicide . It inhibits photosynthesis and the cell division of the plant, which is why the weeds die.

use

It is mainly used against weeds and grass weeds in beet, cabbage, spinach, lettuce and bean cultivation. It can also be used as a plant growth regulator.

Environmental aspects

Propham is toxic to aquatic organisms. The active ingredient can be broken down by hydrolytic cleavage of the ester bond and subsequent decomposition of the phenylcarbamic acid that is formed into aniline and carbon dioxide .

proof

Residues can be determined in plants and soils using the HPTLC method .

Admission status

In the EU and in Germany there are none so far pesticides admitted that this active ingredient contained.

Individual evidence

1. ↑ ^{a b c d} David R. Lide: CRC Handbook of Chemistry and Physics: A Ready-reference Book of Chemical and Physical Data . CRC Press, 1995, ISBN 978-0-8493-0595-5 , pp. 3–346 ( books.google.de ).
2. ↑ ^{a b c d} data sheet Propham at Sigma-Aldrich , accessed on July 13, 2020 ( PDF ).
3. ↑ ^{a b c d e f g} Entry on Propham. In: Römpp Online . Georg Thieme Verlag, accessed on July 13, 2020.