Spirotetramat

Structural formula
General
Surname	Spirotetramat
other names	cis -3- (2,5-dimethylphenyl) -8-methoxy-2-oxo-1-azaspiro [4.5] dec-3-en-4-yl ethyl carbonate; cis -4- (ethoxycarbonyloxy) -8-methoxy-3- (2,5-xylyl) -1-azaspiro [4.5] dec-3-en-2-one;
Molecular formula	C 21 H 27 NO 5
External identifiers / databases
EC number	606-523-6
ECHA InfoCard	100.106.958
PubChem	9969573
Wikidata	Q2685527
properties
Molar mass	373.44 g mol −1
Physical state	firmly
density	1.23 g cm −3
Melting point	142 ° C
boiling point	decomposes at 235 ° C
solubility	practically insoluble in water (0.03 g l −1 at 20 ° C and pH 7); easily soluble in dichloromethane ;
safety instructions
H and P phrases	H: 361fd-317-319-335-410
	P: 280
Toxicological data	> 2000 mg kg −1 ( LD 50 , rat , oral ) ; > 2000 mg kg −1 ( LD 50 , rat , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Spirotetramat is a chemical compound from the group of tetramic acid derivatives and carbonic acid esters . It is used as an insecticide and is one of the ACC inhibitors that interrupt lipid biosynthesis .

Mode of action

Spirotetramat is an ambimobile insecticide, i. H. it is transported both up and down through the vascular bundles.

Admission

In 2013, the EU Commission decided to include Spirotetramat in the list of active ingredients permitted for plant protection products. In Germany, Austria and Switzerland, Spirotetramat is available under the trade name Movento.

toxicity

Spirotetramat is only slightly acutely toxic to humans . It is irritating to the eyes and has a potential to sensitize the skin . No carcinogenic effects could be demonstrated in experiments on rats . Spirotetramat is toxic to aquatic invertebrates and bees .

Individual evidence

↑ ^a ^b ^c ^d ^e SPIROTETRAMAT (234) (PDF; 2.5 MB) from the FAO.
↑ Entry on Spirotetramat in the GESTIS substance database of the IFA , accessed on July 23, 2016(JavaScript required) .
↑ Entry on Spirotetramat in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Data sheet Spirotetramat, PESTANAL at Sigma-Aldrich , accessed on August 15, 2013 ( PDF ).
↑ ^a ^b Pesticide Fact Sheet: Spirotetramat (PDF; 434 kB).
↑ Implementing Regulation (EU) No. 1177/2013 of November 20, 2013 (PDF)
↑ General Directorate Health and Food Safety of the European Commission: Entry on Spirotetramat in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; Retrieved February 19, 2016.

↑ EPO Pesticide Fact Sheet, June 2008. Retrieved January 23, 2018 .

[fao-1] SPIROTETRAMAT (234) (PDF; 2.5 MB) from the FAO.

[GESTIS-2] Entry on Spirotetramat in the GESTIS substance database of the IFA , accessed on July 23, 2016(JavaScript required) .

[CLP_100.106.958-3] Entry on Spirotetramat in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[Sigma-4] Data sheet Spirotetramat, PESTANAL at Sigma-Aldrich , accessed on August 15, 2013 ( PDF ).

[epa-5] Pesticide Fact Sheet: Spirotetramat (PDF; 434 kB).

[eu-6] Implementing Regulation (EU) No. 1177/2013 of November 20, 2013 (PDF)

[PSM-7] General Directorate Health and Food Safety of the European Commission: Entry on Spirotetramat in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; Retrieved February 19, 2016.

[8] EPO Pesticide Fact Sheet, June 2008. Retrieved January 23, 2018 .