Sulfosulfuron

Structural formula
General
Surname	Sulfosulfuron
other names	1- (4,6-Dimethoxypyrimidin-2-yl) -3- (2-ethylsulfonylimidazo- (1,2-a) pyridin-3-yl) sulfonylurea
Molecular formula	C 16 H 18 N 6 O 7 S 2
Brief description	White dust
External identifiers / databases
EC number	604-251-2
ECHA InfoCard	100.117.330
PubChem	86426
ChemSpider	77941
Wikidata	Q2364499
properties
Molar mass	470.47 g mol −1
Physical state	firmly
density	1.5185 g cm -
Melting point	201.1-201.7 ° C ° C
Vapor pressure	0.0000305 mPa (20 ° C)
solubility	poorly soluble in water (1.6 g / l at pH 7 and 20 ° C) and 1,2-dichloromethane (4.35 g / l)
safety instructions
GHS hazard labeling from Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary Caution
H and P phrases	H: 410
	P: 273-501
Toxicological data	> 5000 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Sulfosulfuron is a chemical compound from the group of sulfonylureas (more precisely the pyrimidinylsulfonylureas).

properties

Sulfosulfuron is a white powder that is poorly soluble in water.

use

Sulfosulfuron is used as an active ingredient in crop protection products. It is used as a post-emergence herbicide to control bristle species and couch grass as well as certain broad-leaved weeds in winter wheat and triticale . The action is based on the inhibition of acetolactate synthase (ALS), an enzyme that is involved in the synthesis of the amino acids isoleucine, valine and leucine in susceptible plants.

Admission

The application for approval in the EU was submitted by Monsanto on April 24, 1997 . With effect from July 1, 2002, sulfosulfuron was approved for use as a herbicide. The approval as an active ingredient was extended in 2011 to the end of 2015. In Switzerland pesticides (e.g. monitor) with this active ingredient are approved, in Germany and Austria none.

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j EU: Review report for the active substance sulfosulfuron (PDF; 323 kB), July 2, 2002.
↑ ^a ^b Entry on sulfosulfuron in the GESTIS substance database of the IFA , accessed on July 29, 2012(JavaScript required) .
↑ Entry on 1- (4,6-dimethoxypyrimidin-2-yl) -3- (2-ethylsulfonylimidazo [1,2-a] pyridin-3-yl) sulfonylurea Template: Linktext-Check / Escaped in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ data sheet sulfosulfuron at Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).
^ Edited by Terence Robert Roberts, David Herd Hutson: Metabolic Pathways of Agrochemicals: Herbicides and plant growth regulators . Royal Society of Chemistry, 1998, ISBN 0-85404-494-9 , pp. 555 ( limited preview in Google Book search).
↑ Monsanto: MONITOR - the herbicide against wind stalks, Trespe and couch grass
↑ Thomas A. Monaco, J. Earl Creech: Sulfosulfuron effects on growth and photosynthesis of 15 range grasses In: J. Range Manage . 57 ( 5 ): 490-496. 2004.
↑ Directive 2002/48 / EC of the Commission of May 30, 2002 amending Council Directive 91/414 / EEC and including the active substances Iprovalicarb, Prosulfuron and Sulfosulfuron (PDF)
↑ Implementing Regulation (EU) No. 540/2011 of the Commission of 25 May 2011 for the implementation of Regulation (EC) No. 1107/2009 of the European Parliament and of the Council with regard to the list of approved active substances (PDF)
^ Directorate-General for Health and Food Safety of the European Commission: Entry on sulfosulfuron in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 13, 2016.

[EU-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j EU: Review report for the active substance sulfosulfuron (PDF; 323 kB), July 2, 2002.

[GESTIS-2] Entry on sulfosulfuron in the GESTIS substance database of the IFA , accessed on July 29, 2012(JavaScript required) .

[CLP_100.117.330-3] Entry on 1- (4,6-dimethoxypyrimidin-2-yl) -3- (2-ethylsulfonylimidazo [1,2-a] pyridin-3-yl) sulfonylurea Template: Linktext-Check / Escaped in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[Sigma-4] ta sheet sulfosulfuron at Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).

[herausgegeben_von_Terence_Robert_Roberts,David_Herd_Hutson-5] Edited by Terence Robert Roberts, David Herd Hutson: Metabolic Pathways of Agrochemicals: Herbicides and plant growth regulators . Royal Society of Chemistry, 1998, ISBN 0-85404-494-9 , pp. 555 ( limited preview in Google Book search).

[Monsanto-6] Monsanto: MONITOR - the herbicide against wind stalks, Trespe and couch grass

[7] Thomas A. Monaco, J. Earl Creech: Sulfosulfuron effects on growth and photosynthesis of 15 range grasses In: J. Range Manage . 57 ( 5 ): 490-496. 2004.

[8] Directive 2002/48 / EC of the Commission of May 30, 2002 amending Council Directive 91/414 / EEC and including the active substances Iprovalicarb, Prosulfuron and Sulfosulfuron (PDF)

[9] Implementing Regulation (EU) No. 540/2011 of the Commission of 25 May 2011 for the implementation of Regulation (EC) No. 1107/2009 of the European Parliament and of the Council with regard to the list of approved active substances (PDF)

[PSM-10] Directorate-General for Health and Food Safety of the European Commission: Entry on sulfosulfuron in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 13, 2016.