Tepraloxydim

Structural formula
General
Surname	Tepraloxydim
other names	( RS ) - ( EZ ) -2- (1 - ((2 E ) -3-chlorallyloxyimino) propyl) -3-hydroxy-5-perhydropyran-4-ylcyclohex-2-en-1-one
Molecular formula	C 17 H 24 ClNO 4
Brief description	Solid
External identifiers / databases
EC number	604-715-4
ECHA InfoCard	100.113.792
PubChem	6259842
Wikidata	Q22808950
properties
Molar mass	341.83 g mol −1
Physical state	firmly
density	1.28 g cm −3 (bulk density)
Melting point	74 ° C
boiling point	> 185 ° C
Vapor pressure	1.1 · 10 −7 hPa (20 ° C)
solubility	practically insoluble in water (0.43 g l −1 at 20 ° C); soluble in dichloromethane (1190 g l −1 ), toluene (820 g l −1 ) and acetonitrile (770 g l −1 );
safety instructions
GHS hazard labeling from Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary Caution
H and P phrases	H: 351-361fd
	P: 201-308 + 313
Toxicological data	> 2000 mg kg −1 ( LD 50 , rat , oral ) ; > 200 µg bee −1 in 48h ( LD 50 , bee , oral ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Tepraloxydim is a chemical compound from the group of cyclohexene oximes (cyclohexadione).

properties

Tepraloxydim is a solid. It is stable to hydrolysis at a pH of 7 to 9 and slowly decomposes at a pH of 5 ( DT ₅₀ = 22.1 days).

use

Tepraloxydim is used as a herbicide (for example under the name Aramo) in arable farming (beets, rape, potatoes), in forestry and in ornamental plants. It is an acetyl-CoA carboxylase inhibitor.

In the EU there are none pesticides approved with the active ingredient tepraloxydim. Nevertheless, tepraloxydim can be manufactured in the EU for export .

proof

After derivatization, the active ingredient can be determined using gas chromatography and directly using LC- (ESI +) - MS / MS.

Web links

Review of the existing maximum residue levels (MRLs) for tepraloxydim according to Article 12 of Regulation (EC) No 396/2005. In: EFSA Journal. 9, 2011, p. 2423, doi : 10.2903 / j.efsa.2011.2423 .

Individual evidence

↑ ^a ^b ^c ^d Entry on Tepraloxydim in the GESTIS substance database of the IFA , accessed on December 30, 2019(JavaScript required) .
↑ ^a ^b ^c ^d ^e Entry on tepraloxydim (Ref: BAS 620H) in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on August 6, 2017.
↑ ^a ^b ^c ^d ^e ^f biosicherheit-bch.de: Tepraloxydim , accessed on August 6, 2017
↑ Entry on (RS) - (EZ) -2- {1 - [(2E) -3-chloroallyloxyimino] propyl} -3-hydroxy-5-perhydropyran-4-ylcyclohex-2-en-1-one in the Classification and Labeling inventory of the European Chemicals Agency (ECHA), accessed on December 30, 2019. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Tepraloxydim data sheet , PESTANAL at Sigma-Aldrich , accessed on December 30, 2019 ( PDF ).
↑ General Directorate Health and Food Safety of the European Commission: Entry on Tepraloxydim in the EU pesticide database ; accessed on October 1, 2019.

↑ Maurin Jost: Export of harmful pesticides: A lot of poison for abroad. In: taz.de . September 29, 2019, accessed October 1, 2019 .

[GESTIS-1] Entry on Tepraloxydim in the GESTIS substance database of the IFA , accessed on December 30, 2019(JavaScript required) .

[PPDB-2] Entry on tepraloxydim (Ref: BAS 620H) in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on August 6, 2017.

[biosicherheit-bch.de-3] ↑ ^a ^b ^c ^d ^e ^f biosicherheit-bch.de: Tepraloxydim , accessed on August 6, 2017

[CLP_100.113.792-4] Entry on (RS) - (EZ) -2- {1 - [(2E) -3-chloroallyloxyimino] propyl} -3-hydroxy-5-perhydropyran-4-ylcyclohex-2-en-1-one in the Classification and Labeling inventory of the European Chemicals Agency (ECHA), accessed on December 30, 2019. Manufacturers or distributors can expand the harmonized classification and labeling .

[Sigma-5] Tepraloxydim data sheet , PESTANAL at Sigma-Aldrich , accessed on December 30, 2019 ( PDF ).

[PSM-6] General Directorate Health and Food Safety of the European Commission: Entry on Tepraloxydim in the EU pesticide database ; accessed on October 1, 2019.

[7] Maurin Jost: Export of harmful pesticides: A lot of poison for abroad. In: taz.de . September 29, 2019, accessed October 1, 2019 .