Tetraethylammonium chloride

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Structural formula
Structural formula of tetraethylammonium chloride
General
Surname Tetraethylammonium chloride
other names
  • TEA chloride
  • TEAC
Molecular formula C 8 H 20 ClN
Brief description

colorless to light yellow solid

External identifiers / databases
CAS number
  • 56-34-8
  • 68696-18-4 (monohydrate)
  • 6024-76-6 (tetrahydrate)
EC number 200-267-5
ECHA InfoCard 100,000,243
PubChem 5946
ChemSpider 5733
Wikidata Q7706336
properties
Molar mass 165.71 g mol −1
Physical state

firmly

density

1.08 g cm −3 (tetrahydrate)

Melting point
  • 360 ° C
  • 37 ° C (tetrahydrate)
solubility

soluble in water, ethanol , chloroform or acetone

safety instructions
GHS labeling of hazardous substances
07 - Warning

Caution

H and P phrases H: 315-319-335
P: 261-280-305 + 351 + 338-304 + 340-405-501
Toxicological data

2630 mg kg −1 ( LD 50 ,  rat ,  oral )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Tetraethylammonium chloride is a chemical compound from the group of quaternary ammonium compounds .

Extraction and presentation

Tetraethylammonium chloride can be obtained by reacting triethylamine and ethyl chloride or by reacting tetraethylammonium iodide and mercury (I) chloride .

properties

Tetraethylammonium chloride is a colorless to light yellow solid that is soluble in water, ethanol, chloroform or acetone. The compound is amphiphilic . It has a monoclinic crystal structure with the space group P 2 1 / c (space group no. 14) . Template: room group / 14

use

Tetraethylammonium chloride is used as a catalyst. It can also be used as a source of tetraethylammonium ions for various pharmaceutical studies and has the ability to block K + channels in various tissues. Tetraethylammonium chloride can also block the transmission of nerve impulses through autonomic ganglia.

Individual evidence

  1. ↑ a b c Datasheet Tetraethylammonium chloride, for electrochemical analysis, ≥99.0% from Sigma-Aldrich , accessed on November 2, 2018 ( PDF ).
  2. ↑ a b c d e f g Datasheet Tetraethylammonium chloride from AlfaAesar, accessed on November 2, 2018 ( PDF )(JavaScript required) .
  3. ↑ a b Z: Römpp Lexikon Chemie, 10th edition, 1996-1999 Volume 6: T - Z . Georg Thieme Verlag, 2014, ISBN 978-3-13-200071-1 ( limited preview in Google book search).
  4. ↑ Arthur A. Vernon, Gershon M. Goldberg, John H. LaRochelle: The Solubility of Tetraethylammonium Chloride in Benzene-Ethylene Dichloride Mixtures. In: Journal of the American Chemical Society . 73, 1951, p. 2844, doi : 10.1021 / ja01150a122 .
  5. ↑ Yoshikata Koga, Fumie Sebe, Keiko Nishikawa: Effects of Tetramethyl- and Tetraethylammonium Chloride on H 2 O: Calorimetric and Near-Infrared Spectroscopic Study. In: Journal of Physical Chemistry B . 117, 2013, p. 877, doi : 10.1021 / jp3082744 .
  6. ↑ RJ Staples: Crystal structure of anhydrous tetraethylammonium chloride, [(CH 3 CH 2 ) 4 N] Cl. In: Journal of Crystallography - New Crystal Structures . 214, 1999, doi : 10.1515 / ncrs-1999-0241 .