Tetraethylene glycol dimethyl ether

Structural formula
General
Surname	Tetraethylene glycol dimethyl ether
other names	Bis (2- (2-methoxyethoxy) ethyl) ether Dimethoxytetraglycol Dimethyl tetraglycol 2,5,8,11,14-pentaoxapentadecane Tetraglyme TGDE
Molecular formula	C 10 H 22 O 5
Brief description	colorless liquid with an ethereal odor
External identifiers / databases
CAS number 143-24-8 EC number 205-594-7 ECHA InfoCard 100.005.086 PubChem 8925 ChemSpider 13835433 DrugBank DB14000 Wikidata Q3788669
properties
Molar mass	222.28 g mol −1
Physical state	liquid
density	1.01 g cm −3
Melting point	−30 ° C
boiling point	274-275 ° C
Vapor pressure	0.099 Pa (20 ° C)
solubility	miscible with water soluble in ethanol and carbon tetrachloride
Refractive index	1.432 (20 ° C)
safety instructions
GHS labeling of hazardous substances danger H and P phrases H: 360Df P: 201-308 + 313
Toxicological data	5140 mg kg −1 ( LD 50 ,  rat ,  oral )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

Tetraethylene glycol dimethyl ether is a chemical compound from the group of glycol ethers .

Extraction and presentation

Tetraethylene glycol dimethyl ether can be obtained by a Williamson ether synthesis of tetraethylene glycol with methyl chloride and alkaline hydroxides .

properties

Tetraethylene glycol dimethyl ether is a flammable, hardly inflammable, little volatile, colorless liquid with an ethereal odor, which is miscible with water.

use

Tetraethylene glycol dimethyl ether can be used as a coating material on glucose sensors and as an electrolyte in lithium-ion batteries. In addition, it is a suitable solvent for high temperature reactions due to its high boiling point. It is also used in the selective adsorption of proteins while promoting cell adhesion.

Individual evidence

1. ↑ ^{a b c d e f g h i j k} Entry on tetraethylene glycol dimethyl ether in the GESTIS substance database of the IFA , accessed on January 10, 2017(JavaScript required) .
2. ^ GWA Milne: Gardner's Commercially Important Chemicals Synonyms, Trade Names, and Properties . John Wiley & Sons, 2005, ISBN 0-471-73661-9 , pp. 609 ( limited preview in Google Book search).
3. ↑ ^{a b} Datasheet Tetraethylene glycol dimethyl ether, ≥99% from Sigma-Aldrich , accessed on July 13, 2016 ( PDF ).
4. ↑ cnki.com.cn: Synthesis of Tetraethylene Glycol Dimethyl Ether by Williamson Reaction , accessed July 13, 2016.
5. ↑ Datasheet Tetraethylene glycol dimethyl ether, 98 +% from AlfaAesar, accessed on July 13, 2016 ( PDF )(JavaScript required) .