Tetraethylene glycol

Structural formula
General
Surname	Tetraethylene glycol
other names	3,6,9-trioxaundecane-1,11-diol 2,2 '- [oxybis (ethyleneoxy)] diethanol
Molecular formula	C 8 H 18 O 5
Brief description	colorless and odorless liquid
External identifiers / databases
CAS number 112-60-7 EC number 203-989-9 ECHA InfoCard 100.003.627 PubChem 8200 Wikidata Q12430182
properties
Molar mass	194.23 g mol −1
Physical state	liquid
density	1.12 g cm −3
Melting point	−6 ° C
boiling point	327 ° C
Vapor pressure	0.01 hPa (20 ° C)
solubility	miscible with water
Refractive index	1.4593 (20 ° C)
safety instructions
GHS labeling of hazardous substances no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
Toxicological data	> 20000 mg kg −1 ( LD 50 ,  rabbit ,  transdermal ) 32500 mg kg −1 ( LD 50 ,  rat ,  oral )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

Tetraethylene glycol is a chemical compound from the group of glycol ethers .

Extraction and presentation

Tetraethylene glycol is obtained as a by-product in the synthesis of di- and triethylene glycol from ethylene oxide and ethylene glycol in the presence of acids or in the production of ethylene glycol by hydrolysis of ethylene oxide.

properties

Tetraethylene glycol is a very difficult to ignite, not very volatile, colorless and odorless liquid that is miscible with water. It is less hygroscopic than mono- and diethylene glycol and can only be mixed to a limited extent with alcohols, ketones and alkanolamines in any ratio and with diethyl ether.

use

Tetraethylene glycol is used as a plasticizer for cell glass and nitrocellulose lacquers, as a drying agent for natural and industrial gas, as a heat transfer fluid or humectant for cork. It is a starting material for the production of synthetic resins , plasticizers, emulsifiers and adhesives, especially of tetraethylene glycol di (meth) acrylates by esterification . Tetraethylene glycol is also used as a solvent and lubricant for dyeing and printing textiles, as a lubricant for rubber and as an extractant for aromatics and is a component in printing inks, soldering aids and hydraulic oils . It is used in pharmaceutical and cosmetic preparations and cleaning agents. In organic chemistry, tetraethylene glycol is suitable for the production of crown ethers , as a precursor to linkers in combinatorial chemistry and for the immobilization of biomolecules.

Individual evidence

1. ↑ ^{a b c d e f g h i j k} Entry for CAS no. 112-60-7 in the GESTIS substance database of the IFA , accessed on September 6, 2015(JavaScript required) .
2. ↑ ^{a b c d} Entry on tetraethylene glycol. In: Römpp Online . Georg Thieme Verlag, accessed on September 6, 2015.