Thiodiglycol
Structural formula | |||||||||||||||||||
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General | |||||||||||||||||||
Surname | Thiodiglycol | ||||||||||||||||||
other names |
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Molecular formula | C 4 H 10 O 2 S | ||||||||||||||||||
Brief description |
colorless liquid |
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properties | |||||||||||||||||||
Molar mass | 122.18 g mol −1 | ||||||||||||||||||
Physical state |
liquid |
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density |
1.18 g cm −3 |
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Melting point |
−16 ° C |
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boiling point |
282 ° C |
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Vapor pressure |
0.11 Pa (20 ° C) |
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solubility |
miscible with water |
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Refractive index |
1.5211 (20 ° C) |
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safety instructions | |||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C |
Thiodiglycol or bis (2-hydroxyethyl) sulfide , also 2,2'-sulfanediyldiethanol, is a precursor product in the production of mustard gas ( mustard ). The bis (2-hydroxyethyl) sulfide is chlorinated to mustard by heating with thionyl chloride in a benzene solution.
Under the synonymous name 2,2′-thiodiethanol, thiodiglycol is used as an embedding medium in light microscopy . Since it is miscible with water, the refractive index can be continuously adjusted between that of water (1.33) and that of immersion oil (1.52).
Thiodiglycol is also used as a solvent for dyes, where it increases the color intensity and dispersibility.
Individual evidence
- ↑ a b c d e f g h Entry on 2,2′-thiodiethanol in the GESTIS substance database of the IFA , accessed on February 19, 2017(JavaScript required) .
- ↑ David R. Lide (Ed.): CRC Handbook of Chemistry and Physics . 90th edition. (Internet version: 2010), CRC Press / Taylor and Francis, Boca Raton, FL, Physical Constants of Organic Compounds, pp. 3-52.
- ↑ Entry on thiodiglycol in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
- ↑ Thorsten Staudt, Marion C. Lang, Rebecca Medda, Johann Engelhardt, Stefan Hell : 2,2-Thiodiethanol: A new water soluble mounting medium for high resolution optical microscopy . In: Microsc Res Tech . , 2007 Jan, 70 (1), pp. 1-9, PMID 17131355 , DOI: 10.1002 / jemt.20396 .
- ↑ Entry on 2,2′-sulfanediyldiethanol. In: Römpp Online . Georg Thieme Verlag, accessed on December 6, 2014.