Thiosemicarbazide

Structural formula
General
Surname	Thiosemicarbazide
other names	Hydrazine carbothioamide; Thiocarbamic acid hydrazide; Aminothiourea;
Molecular formula	CH 5 N 3 S
Brief description	white to yellowish powder with a faint odor
External identifiers / databases
EC number	201-184-7
ECHA InfoCard	100.001.077
PubChem	2723789
Wikidata	Q16295007
properties
Molar mass	91.14 g mol −1
Physical state	firmly
density	1.42 g cm −3
Melting point	181 ° C
boiling point	Decomposition from 178 ° C
solubility	heavy in water (13 g l −1 at 20 ° C); easily in hot water (187 g l −1 at 80 ° C); very little in organic solvents;
safety instructions
GHS labeling of hazardous substances danger
H and P phrases	H: 300
	P: 264-301 + 310
Toxicological data	9.16 mg kg −1 ( LD 50 , rat , oral ) ; 2200 mg kg −1 ( LD 50 , rabbit , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Thiosemicarbazide is a chemical compound and an amino derivative of thiourea .

Extraction and presentation

It can be made by heating an aqueous solution of ammonium thiocyanate with hydrazinium sulfate and sodium hydroxide .

Thiosemicarbazide is used as an antioxidant , corrosion inhibitor , stabilizer in photography and as a raw material for the manufacture of pharmaceuticals (tuberculostatic thioacetazone and virostatic methisazone ).

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ Entry on thiosemicarbazide in the GESTIS substance database of the IFA , accessed on January 8, 2018(JavaScript required) .
↑ ^a ^b ^c ^d Entry on thiosemicarbazide. In: Römpp Online . Georg Thieme Verlag, accessed on March 18, 2014.