Tralopyril

Structural formula
General
Surname	Tralopyril
other names	4-Bromo-2- (4-chlorophenyl) -5- (trifluoromethyl) -1 H -pyrrole-3-carbonitrile ( IUPAC )
Molecular formula	C 12 H 5 BrClF 3 N 2
External identifiers / databases
EC number	602-784-5
ECHA InfoCard	100.125.440
PubChem	183559
Wikidata	Q17326630
properties
Molar mass	349.53 g mol −1
Physical state	firmly
density	1.714 g cm −3
Melting point	253.4 ° C , decomposes above 230 ° C
Vapor pressure	0.000019 mPa (20 ° C)
solubility	practically insoluble in water (0.17 g l −1 at 20 ° C and pH 8.1); Easily soluble in acetone (300 g l −1 ), ethyl acetate (236 g l −1 ) and methanol (109 g l −1 );
safety instructions
GHS labeling of hazardous substances Caution
H and P phrases	H: 410
	P: 273-501
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Tralopyril is a chemical compound from the azole group , which is an effective molluscicide . The compound was first patented by American Cyanamid and now by Janssen Pharmaceutica .

use

Together with an algicide , Tralopyril can be used as an underwater paint . It is as effective against animals as the metallic active substances (such as copper or zinc pyrithione ), but less toxic. The 1- (ethoxymethyl) -substituted derivative of tralopyril is the insecticide chlorfenapyr .

With a bioconcentration factor of less than 3.2, tralopyril is practically non- bioaccumulative .

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g Efficacy, chemistry and environmental fate of tralopyril, a non-metal antifouling agent February 28, 2011.
↑ ^a ^b data sheet Tralopyril from Sigma-Aldrich , accessed on May 22, 2017 ( PDF ).
↑ Patent EP0746979 : Use of pyrrole compounds as antifouling agents (use of pyrrole compounds as an antifouling agent). Published December 11, 1996 , Applicant: American Cyanamid, Inventor: Mark Arthur Josepha van der Flaas, Stephen Crawley Lantz. ‌
↑ patent WO2013131940 : Use of tralopyril against marine woodborers. Published on September 12, 2013 , Applicant: Janssen Pharmaceutica, Inventor: van der Flaas, David Bruce Helmer, Jan Remi Nys. ‌
↑ Janssen Econea ( Memento of the original from March 4, 2016 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2

[kempen-1] ↑ ^a ^b ^c ^d ^e ^f ^g Efficacy, chemistry and environmental fate of tralopyril, a non-metal antifouling agent February 28, 2011.

[Sigma-2] ta sheet Tralopyril from Sigma-Aldrich , accessed on May 22, 2017 ( PDF ).

[3] Patent EP0746979 : Use of pyrrole compounds as antifouling agents (use of pyrrole compounds as an antifouling agent). Published December 11, 1996 , Applicant: American Cyanamid, Inventor: Mark Arthur Josepha van der Flaas, Stephen Crawley Lantz. ‌

[4] tent WO2013131940 : Use of tralopyril against marine woodborers. Published on September 12, 2013 , Applicant: Janssen Pharmaceutica, Inventor: van der Flaas, David Bruce Helmer, Jan Remi Nys. ‌

[5] Janssen Econea ( Memento of the original from March 4, 2016 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2