Wolff Schmiegel

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Wolff Schmiegel (born September 25, 1951 in Wanne-Eickel ) is a German specialist in internal medicine , gastroenterology , endocrinology , hematology / internal oncology , director of the medical clinic at the University Clinic Knappschaftskrankenhaus Bochum until his retirement in 2019 and also director from 2002 to 2019 the department of gastroenterology / hepatology at the Bergmannsheil University Hospital in Bochum.

Life

Schmiegel studied medicine from 1970 to 1977 at the University of Leuven / Belgium , at the Ruhr University Bochum and the Rheinische Friedrich-Wilhelms-Universität Bonn . The doctorate took place in 1978 at the University of Essen . From 1978 to 1990 he was a research assistant at the Medical Clinic, UKE Hamburg, and was recognized as a doctor for internal medicine. In 1988 he completed his habilitation in internal medicine at the UKE Hamburg. After his employment as senior physician at the I. Medical University Clinic and Polyclinic at the University Medical Center Hamburg-Eppendorf , he was appointed to a C3 professorship (gastroenterology / hepatology / gastroenterological oncology) by the University of Hamburg in 1993, and subsequently an appointment as university professor and director of the medical university clinic Knappschaftskrankenhaus , Ruhr University Bochum and in 2002 as director of the department for gastroenterology / hepatology at the professional association University Hospital Bergmannsheil . From 1999 to 2003 and from 2007 to 2009 he was medical director of the University Clinic Knappschaftskrankenhaus Bochum. Ali Canbay, who previously headed the Gastroenterology, Hepatology and Infectious Disease Clinic at Magdeburg University Hospital, succeeded him in 2019 as director of the medical clinic at the University Clinic Knappschaftskrankenhaus Bochum.

Clinical-scientific focus

From 1978 to 1981 Schmiegel worked in the Department of Clinical Immunology at the University Hospital Eppendorf on a tumor immunological scientific focus with the generation of tumor-specific monoclonal antibodies against pancreatic and colon carcinoma cell structures. An anti EGF receptor-specific monoclonal antibody was initially used preclinically and subsequently also clinically for the first time in pancreatic cancer patients. In 1999 Schmiegel coordinated the first oncological S3 evidence-based guideline for colorectal cancer, which was the basis for the introduction of colon cancer screening and colonoscopy (2002) by the GBA. This was followed by the continuation of clinical therapy studies for gastrointestinal tumors as well as work on improving colon cancer early detection and the detection of risk patients as a center for familial colon cancer of the German Cancer Aid. It was possible to identify prognostic and predictive biomarkers for gastroenterological tumor diseases and their clinical use was also tested with the so-called liquid biopsy .

Positions

  • 2016–2021 Board of Trustees - German Cancer Aid Foundation
  • 2016–2019 Board Member - State Cancer Society NRW
  • 2012–2016 President - German Cancer Society
  • 2012–2019 Board of Directors - European Society of Digestive Oncology (ESDO)
  • 2011 - Fellow - American Gastroenterological Association (AGAF)
  • 2010 Congress President of the German Cancer Society
  • 2009–2012 Member of the Scientific Committee - United European Gastroenterology Foundation (UEGF)
  • 2009–2012 Secretary General - European Society of Digestive Oncology (ESDO), as well as member of the Scientific Committee of the United European Gastroenterology Foundation (UEGF)
  • 2009 - 2017 Steering Committee - National Cancer Plan (BMG, DKG, DKH, ADT)
  • 2008–2016 board member - German Cancer Society
  • 2007 President - German Society for Gastroenterology, Digestive and Metabolic Diseases
  • 2006–2012 Councilor - UEGF
  • 2005–2017 Scientific Advisory Board - IZKF University Clinic Erlangen
  • 2003–2007 steering committee of the National Genome Research Network
  • 2001–2004 Senate Committee of the DFG for Collaborative Research Centers.
  • 1998–2010 Secretary and board member - German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS)
  • 1993–2015 Advisory Board - German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS)
  • 1993–2000 spokesman for the Gastroenterological Oncology Working Group of the DGVS

honors and awards

  • E. Konjetzny Prize of the Hamburg Cancer Society (1988)
  • Dr. Martini Prize of the Dr. Martini Foundation, University Hospital Hamburg (1989)
  • Foundation for the Promotion of Innovation in Science and Research NRW Prize (1994)
  • Charles Moertel Award in Digestive Oncology (International Digestive Cancer Alliance / World Gastroenterology Organization) (2007)
  • Felix Burda Award (2014)
  • Tannhauser Medal of the DGVS 2018

Memberships in scientific specialist societies

Publications

Schmiegel published around 600 medical articles by July 2017 and is co-editor of two standard works on internal medicine and gastroenterology.

Books

  • Adler, Begingen, Manns, Müller-Lissner, Schmiegel, (Ed.): Clinical gastroenterology and metabolism. Springer, 2000/2014
  • M. Böhm, M. Hallek, W. Schmiegel (Eds.): Internal Medicine, Elsevier 2009

Scientific articles

Individual evidence

  1. ^ A b c Medical University Clinic, Knappschaftskrankenhaus Bochum: Wolff Schmiegel
  2. ↑ Elke Bartholomäus: tasks and offices. In: Deutsches Ärzteblatt. Volume 116, Issue 51-52, December 23, 2019, p. B 1979.
  3. ^ Schmiegel W, Schmielau J, Henne-Bruns D, Juhl H, Roeder C, Buggisch P, Onur A, Kremer B, Kalthoff H, Jensen EV. Cytokine-mediated enhancement of epidermal growth factor receptor expression provides an immunological approach to the therapy of pancreatic cancer. Proc Natl Acad Sci U.S.A. 1997 Nov 11; 94 (23): 12622-6.
  4. ↑ Wolff Schmiegel, Rodney J. Scott et al. a .: Blood-based detection of RAS mutations to guide anti-EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue-based RAS testing. In: Molecular Oncology. 11, 2017, p. 208, doi : 10.1002 / 1878-0261.12023 .
  5. ↑ UKRUB: Felix Burda Award goes to Bochum
personal data
SURNAME Schmiegel, Wolff
BRIEF DESCRIPTION German medic
DATE OF BIRTH September 25, 1951
PLACE OF BIRTH Wanne-Eickel