Pantopon: Difference between revisions

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'''Pantopon''', also known as Opium Alkaloids Hydrochlorides, is a preparation of [[opiates]] made up of all of the [[alkaloids]] present in [[opium]] in their natural proportions as [[hydrochloride]]s [[salt (chemistry)|salts]].<ref>{{cite journal | doi = 10.1007/BF01681141 | title = Über die Wirkung von Morphium, Opium und Pantopon auf die Bewegungen des Magen-Darm-Tractus des Menschen und des Tieres | journal = Pflüger's Archiv für die Gesamte Physiologie des Menschen und der Tiere | volume = 151 | issue = 1–3 | pages = 65–96 | year = 1913 | last1 = Schapiro | first1 = Nicolai }}</ref><ref>{{cite journal | doi = 10.1515/bchm2.1911.71.4.273 | title = Zur Wirkung von Morphium und Opiumpräparaten (Pantopon) auf den Verdauungskanal | journal = Hoppe-Seyaler's Zeitschrift für Physiologische Chemie | volume = 71 | issue = 4 | pages = 273–289 | year = 1911 | last1 = Cohnheim | first1 = Otto | last2 = Modrakowski | first2 = Gg. }}</ref><ref>{{Cite journal | doi = 10.1001/jama.1932.02740640028007 | title = The Tranquilizing Potency of Morphine, Pantopon, Codeine, Papaverine and Narcotine | journal = Journal of the American Medical Association | volume = 99 | issue = 12 | pages = 986 | year = 1932 | last1 = Barlow | first1 = O. W. }}</ref> It can sometimes be tolerated by people who are allergic to [[morphine]].
'''Pantopon''', also known as Opium Alkaloids Hydrochlorides, is a preparation of [[opiates]] made up of all of the [[alkaloids]] present in [[opium]] in their natural proportions as [[hydrochloride]]s [[salt (chemistry)|salts]].<ref>{{cite journal | doi = 10.1007/BF01681141 | title = Über die Wirkung von Morphium, Opium und Pantopon auf die Bewegungen des Magen-Darm-Tractus des Menschen und des Tieres | journal = Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere | volume = 151 | issue = 1–3 | pages = 65–96 | year = 1913 | last1 = Schapiro | first1 = Nicolai | s2cid = 30281372 | url = https://zenodo.org/record/2214498 }}</ref><ref>{{cite journal | doi = 10.1515/bchm2.1911.71.4.273 | title = Zur Wirkung von Morphium und Opiumpräparaten (Pantopon) auf den Verdauungskanal | journal = Hoppe-Seyler's Zeitschrift für Physiologische Chemie | volume = 71 | issue = 4 | pages = 273–289 | year = 1911 | last1 = Cohnheim | first1 = Otto | last2 = Modrakowski | first2 = Gg. | url = https://zenodo.org/record/1866132 }}</ref><ref>{{Cite journal | doi = 10.1001/jama.1932.02740640028007 | title = The Tranquilizing Potency of Morphine, Pantopon, Codeine, Papaverine and Narcotine | journal = Journal of the American Medical Association | volume = 99 | issue = 12 | pages = 986 | year = 1932 | last1 = Barlow | first1 = O. W. }}</ref> It can sometimes be tolerated by people who are allergic to [[morphine]].


Pantopon is prepared by treating standardized medicinal opium with hydrochloric acid or, more commonly, mixing 20 parts morphine HCl, 5 parts codeine, 6 parts thebaine, 8 parts noscapine, 2 parts narcotine, 6 parts miscellaneous alkaloids hydrochlorides.<ref>Inside Narcotics S , pp 131, "Pantopon, Omnopon, and Other Opium Products (Whole)"</ref><ref>The Power of the Poppy, Kenaz Filan, 2015 </ref>
Pantopon is prepared by treating standardized medicinal opium with [[hydrochloric acid]] or, more commonly, mixing 20 parts morphine HCl, 5 parts codeine, 6 parts thebaine, 8 parts noscapine, 2 parts narcotine, 6 parts miscellaneous alkaloids hydrochlorides.<ref>Inside Narcotics S , pp 131, "Pantopon, Omnopon, and Other Opium Products (Whole)"</ref><ref>The Power of the Poppy, Kenaz Filan, 2015</ref>


Pantopon is, in other words, [[opium]] with all of the tar and other insolubles removed in an injectable form which, by weight, is nearly as potent as [[morphine]]. It was invented in 1909 by the [[Hoffmann-La Roche]] pharmaceutical company. Other drugs of the same type have included in the opium alkaloid [[hydrobromide]]s, [[sulfate]]s ([[Papaveretum]]), [[phosphates]], and [[valerates]]. "Opium in a syringe " and "Injectable Whole Opium" were common advertising slogans for the product from Roche. <ref>https://www.curezone.org/upload/_G_H_Forums/History/Opium_Injectable_Whole_Opium_From_The_Juice_Of_The_Poppy_Seeds_by_Pantopon_Roche.jpg</ref>
Pantopon is, in other words, [[opium]] with all of the tar and other insolubles removed in an injectable form which, by weight, is nearly as potent as [[morphine]]. It was invented in 1909 by the [[Hoffmann-La Roche]] pharmaceutical company. Other drugs of the same type have included in the opium alkaloid [[hydrobromide]]s, [[sulfate]]s, [[phosphates]], and [[valerates]]. "Opium in a syringe " and "Injectable Whole Opium" were common advertising slogans for the product from Roche. An example of similar product to Pantopon is Omnopon, which contains morphine, codeine, and papaverine.<ref>https://www.curezone.org/upload/_G_H_Forums/History/Opium_Injectable_Whole_Opium_From_The_Juice_Of_The_Poppy_Seeds_by_Pantopon_Roche.jpg {{Bare URL image|date=March 2022}}</ref>


==Society and culture==
==Society and culture==

Latest revision as of 18:23, 26 October 2023

Pantopon, also known as Opium Alkaloids Hydrochlorides, is a preparation of opiates made up of all of the alkaloids present in opium in their natural proportions as hydrochlorides salts.[1][2][3] It can sometimes be tolerated by people who are allergic to morphine.

Pantopon is prepared by treating standardized medicinal opium with hydrochloric acid or, more commonly, mixing 20 parts morphine HCl, 5 parts codeine, 6 parts thebaine, 8 parts noscapine, 2 parts narcotine, 6 parts miscellaneous alkaloids hydrochlorides.[4][5]

Pantopon is, in other words, opium with all of the tar and other insolubles removed in an injectable form which, by weight, is nearly as potent as morphine. It was invented in 1909 by the Hoffmann-La Roche pharmaceutical company. Other drugs of the same type have included in the opium alkaloid hydrobromides, sulfates, phosphates, and valerates. "Opium in a syringe " and "Injectable Whole Opium" were common advertising slogans for the product from Roche. An example of similar product to Pantopon is Omnopon, which contains morphine, codeine, and papaverine.[6]

Society and culture[edit]

Pantopon gave its name to the poem "Pantopon Rose" by the American writer William Burroughs[7] and to a song with the same name by the Northern Ireland alternative metal band Therapy? on their 1994 album Troublegum. Pantopon also gave its name to the 1996 Mexican documentary Rosa Pantopon.[8]

References[edit]

  1. ^ Schapiro, Nicolai (1913). "Über die Wirkung von Morphium, Opium und Pantopon auf die Bewegungen des Magen-Darm-Tractus des Menschen und des Tieres". Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere. 151 (1–3): 65–96. doi:10.1007/BF01681141. S2CID 30281372.
  2. ^ Cohnheim, Otto; Modrakowski, Gg. (1911). "Zur Wirkung von Morphium und Opiumpräparaten (Pantopon) auf den Verdauungskanal". Hoppe-Seyler's Zeitschrift für Physiologische Chemie. 71 (4): 273–289. doi:10.1515/bchm2.1911.71.4.273.
  3. ^ Barlow, O. W. (1932). "The Tranquilizing Potency of Morphine, Pantopon, Codeine, Papaverine and Narcotine". Journal of the American Medical Association. 99 (12): 986. doi:10.1001/jama.1932.02740640028007.
  4. ^ Inside Narcotics S , pp 131, "Pantopon, Omnopon, and Other Opium Products (Whole)"
  5. ^ The Power of the Poppy, Kenaz Filan, 2015
  6. ^ https://www.curezone.org/upload/_G_H_Forums/History/Opium_Injectable_Whole_Opium_From_The_Juice_Of_The_Poppy_Seeds_by_Pantopon_Roche.jpg [bare URL image file]
  7. ^ "Pantopon Rose" by William Burroughs on Youtube
  8. ^ Rosa Pantopon on IMDB