2,4-dichlorobenzyl alcohol

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Structural formula
Structural formula of 2,4-dichlorobenzyl alcohol
General
Surname 2,4-dichlorobenzyl alcohol
other names
  • Alcohol 2,4-Dichloro-Benzylicus
  • Dichlorobenzene methanol
  • Dichlorophenylmethanol
  • Dybenal
  • DICHLOROBENZYL ALCOHOL ( INCI )
Molecular formula C 7 H 6 Cl 2 O
Brief description

White dust

External identifiers / databases
CAS number 1777-82-8
EC number 217-210-5
ECHA InfoCard 100.015.646
PubChem 15684
ChemSpider 14918
DrugBank DB13269
Wikidata Q209202
Drug information
ATC code

R02 AA03

properties
Molar mass 177.03 g mol −1
Physical state

firmly

density

1.45 g cm −3 (bulk density)

Melting point

55-58 ° C

solubility

poorly soluble in water (1 g l −1 at 20 ° C)

safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances
05 - Corrosive

danger

H and P phrases H: 318
P: 305 + 351 + 338-313
Toxicological data

2,300 mg kg −1 ( LD 50 ,  mouse ,  oral )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

2,4-dichlorobenzyl alcohol is a chemical compound from the group of double- chlorinated benzyl alcohols .

properties

2,4-dichlorobenzyl alcohol is a white powder that is poorly soluble in water. It crystallizes in the monoclinic crystal system in the space group P 2 1 / c (space group no. 14) with the lattice parameters a = 473.6  pm , b = 1281.8 pm, c = 2485.3 pm and β = 96.852 °. Template: room group / 14

use

2,4-Dichlorobenzyl alcohol, like its isomer 3,4-dichlorobenzyl alcohol, is used as a disinfectant and antiseptic that is used (often together with amylmetacresol or levomenthol ) to treat inflammation in the mouth and throat. It comes in the form of lozenges, a solution or a spray.

Trade names

Hextriletten®, Lidazon®, Strepsils®, neo-angin®, Dobensana®

Individual evidence

  1. ↑ Entry on DICHLOROBENZYL ALCOHOL in the CosIng database of the EU Commission, accessed on March 11, 2020.
  2. ↑ a b c d data sheet 2,4-Dichlorobenzyl alcohol, 99% from Sigma-Aldrich , accessed on September 10, 2011 ( PDF ).
  3. ↑ a b c d data sheet 2,4-dichlorobenzyl alcohol (PDF) from Merck , accessed on September 10, 2011.
  4. ↑ M. Bambagiotti-Alberti, B. Bruni, M. Di Vaira, V. Giannellini: "(2,4-Dichlorophenyl) methanol", in: Acta Cryst. , 2007 , E63  (1), pp. 275-276. doi: 10.1107 / S1600536806053086
  5. ^ Margitta Albinus: Hager's handbook of pharmaceutical practice . 1930, OCLC 312139501 , p. 1261 ( limited preview in Google Book search).
  6. ↑ Entry on dichlorobenzyl alcohol in the Pharmawiki , accessed on January 28, 2017.