2-amino-2-methylpropanol

Structural formula
General
Surname	2-amino-2-methylpropanol
other names	Isobutanolamine; 2-amino-2-methyl-1-propanol; Dimethyl-2-hydroxyethylamine; β-aminoisobutyl alcohol; AMINOMETHYL PROPANOL ( INCI ) ;
Molecular formula	C 4 H 11 NO
Brief description	colorless solid with an amine-like odor
External identifiers / databases
EC number	204-709-8
ECHA InfoCard	100.004.282
PubChem	11807
Wikidata	Q32703
properties
Molar mass	89.14 g mol −1
Physical state	firmly
density	0.93 g cm −3
Melting point	30 ° C
boiling point	165 ° C
Vapor pressure	2 mbar (30 ° C)
pK s value	9.7
solubility	soluble in water
Refractive index	1.448 (20 ° C)
safety instructions
GHS hazard labeling from Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary danger
H and P phrases	H: 315-318-412
	P: 273-280-305 + 351 + 338
Toxicological data	2900 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

2-Amino-2-methylpropanol is a chemical compound from the group of alcohols .

Extraction and presentation

2-Amino-2-methylpropanol can be obtained by reducing the corresponding nitro compound (which in turn can be obtained from 2-nitropropane and formaldehyde by the Henry reaction ).

properties

2-Amino-2-methylpropanol is a slightly volatile, colorless solid with an amine-like odor that is easily soluble in water.

use

2-Amino-2-methylpropanol is used in the manufacture of dyes and medicines .

Individual evidence

↑ Entry on AMINOMETHYL PROPANOL in the CosIng database of the EU Commission, accessed on February 16, 2020.
↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l Entry on 2-Amino-2-methylpropanol in the GESTIS substance database of the IFA , accessed on January 10, 2017(JavaScript required) .
↑ ^a ^b Data sheet 2-Amino-2-methyl-1-propanol from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).
↑ Entry on 2-amino-2-methylpropanol in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Entry on 2-Amino-2-methylpropanol in the Hazardous Substances Data Bank , accessed on November 12, 2012.

[CosIng-1] Entry on AMINOMETHYL PROPANOL in the CosIng database of the EU Commission, accessed on February 16, 2020.

[GESTIS-2] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l Entry on 2-Amino-2-methylpropanol in the GESTIS substance database of the IFA , accessed on January 10, 2017(JavaScript required) .

[Sigma-3] Data sheet 2-Amino-2-methyl-1-propanol from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).

[CLP_100.004.282-4] Entry on 2-amino-2-methylpropanol in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[HSDB-5] Entry on 2-Amino-2-methylpropanol in the Hazardous Substances Data Bank , accessed on November 12, 2012.