4-nitrophenetol

Structural formula
General
Surname	4-nitrophenetol
other names	4-nitroethoxybenzene p -nitrophenetol
Molecular formula	C 8 H 9 NO 3
Brief description	yellowish, crystalline powder
External identifiers / databases
CAS number 100-29-8 EC number 202-837-9 ECHA InfoCard 100.002.580 PubChem 7495 ChemSpider 7214 Wikidata Q19258093
properties
Molar mass	167.16 g mol −1
Physical state	firmly
density	1.12 g cm −3 (100 ° C)
Melting point	60 ° C
boiling point	283 ° C
safety instructions
GHS labeling of hazardous substances no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
Toxicological data	3300 mg kg −1 ( LD 50 ,  rat ,  oral ) > 7940 mg kg −1 ( LD 50 ,  rabbit ,  transdermal )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

4-Nitrophenetol ( p -nitrophenetol) is a chemical compound that is a nitro- substituted derivative of phenetol .

Extraction and presentation

4-nitrophenetol is produced by etherification of 4-nitrophenol with ethyl chloride .

Alternatively, it can also be obtained by reacting 4-chloronitrobenzene with ethanol and an alkali metal hydroxide.

use

4-Nitrophenetol is a precursor for the production of p -phenetidine .

Individual evidence

1. ↑ ^{a b c d e f g h} Entry for CAS no. 100-29-8 in the GESTIS substance database of the IFA , accessed on December 17, 2014(JavaScript required) .
2. ↑ Vollrath Hopp: Fundamentals of chemical technology: for study and professional training . Wiley-VCH, Weinheim u. a. 2001, ISBN 3-527-29998-X , p. 75.
3. ↑ Patent DE3610707 : Process for the production of 4-nitrophenetol. Registered on March 29, 1986 , published on October 8, 1987 , applicant: Bayer AG, inventor: Josef Kaesbauer, Karlfried Wedemeyer. ‌
4. ↑ Entry on Phenetidine. In: Römpp Online . Georg Thieme Verlag, accessed on December 17, 2014.