Acetyldihydrocodeine

Structural formula
General
Surname	Acetyldihydrocodeine
other names	Acetyl dihydrocodeine; 7,8-dihydrocodeine acetate; 3-methoxy-6-acetoxy- (5 α , 6 α ) -4,5-epoxy-17-methylmorphinan;
Molecular formula	C 20 H 25 NO 4
External identifiers / databases
EC number	223-377-5
ECHA InfoCard	100.021.253
PubChem	5463874
ChemSpider	21106249
DrugBank	DB01538
Wikidata	Q4673302
Drug information
ATC code	R05 DA12
Drug class	Antitussive , analgesic
Mechanism of action	Opioid
properties
Molar mass	343.42 g · mol -1
Physical state	firmly
safety instructions
	Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS hazard labeling ; no classification available
Toxicological data	91 mg kg −1 ( LD 50 , mouse , sc )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Acetyldihydrocodeine is a substance from the group of opiate - descendants , taken in 1914 by the German chemist Julius von Braun was discovered. It is regulated as an addictive substance (in Germany: non-marketable narcotics according to the Narcotics Act ) and has a similar effect to other opiates. The analgesic and cough suppressant substance has no therapeutic effect . Acetyldihydrocodeine is chemically very closely related to the morphine derivative thebacone , in which only the 6-7 bond is unsaturated. Acetyldihydrocodeine can be described as the 6-acetyl derivative of dihydrocodeine .

Individual evidence

↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
↑ Entry on acetyldihydrocodeine in the ChemIDplus database of the United States National Library of Medicine (NLM) .
↑ J. v. Braun: Studies on morphine alkaloids. In: Chemical Reports . 47 (2), 1914, pp. 2312-2330, doi : 10.1002 / cber.191404702149 .
^ List of Narcotic Drugs under International Control of the International Narcotic Drugs Control Council (INCB).
↑ Appendix I to the Narcotics Act (BtMG)

[NV-1] This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.

[ChemIDplus-2] Entry on acetyldihydrocodeine in the ChemIDplus database of the United States National Library of Medicine (NLM) .

[3] J. v. Braun: Studies on morphine alkaloids. In: Chemical Reports . 47 (2), 1914, pp. 2312-2330, doi : 10.1002 / cber.191404702149 .

[4] List of Narcotic Drugs under International Control of the International Narcotic Drugs Control Council (INCB).

[5] Appendix I to the Narcotics Act (BtMG)