Alan Hall
Alan Hall (born May 19, 1952 in Barnsley , South Yorkshire , † May 3, 2015 ) was a British cell biologist and researcher at the Memorial Sloan-Kettering Cancer Center in New York City .
Life
Hall earned a bachelor's degree in chemistry from Oxford University in 1974 and a Ph.D. in chemistry with Jeremy Knowles at Harvard University in Cambridge , Massachusetts .
As a postdoctoral fellow he worked with Kenneth Murray (1930–2013) at the University of Edinburgh (1977–1979) and with Charles Weissmann at the University of Zurich (1979–1980), before becoming head of a research group at Chester Beatty Laboratories ( Institute of Cancer Research in London). In 1989 he was appointed professor there and in 1993 he was appointed professor at University College London . In 2001 he became head of the Department of Cell Biology and Molecular Cell Biology at the Medical Research Council . In 2006, he received the Chair of Cell Biology at Memorial Sloan-Kettering Cancer Center in New York City .
Hall died on May 3, 2015 at the age of 62.
Act
Hall is considered to be a pioneer in researching the influence of external signals on the cytoskeleton from proteins such as actin , which in turn influence the shape and mobility ( cell migration ) of the cell. Hall discovered a series of molecular cell switches (the Rho-GTPases ) that play a crucial role in the processes when and where the cell membrane and the cytoskeleton change their order in such a way that this cell moves. Understanding these processes is important for understanding various normal cell and tissue functions, but also the behavior of metastatic tumor diseases.
Awards (selection)
- 1993 Feldberg Foundation Prize
- 1999 membership in the Royal Society
- 2005 Louis Jeantet Prize
- 2006 Gairdner Foundation International Award
literature
- Who's Who in America. 66th Edition, Volume 1: A – L. Marquis Who's Who, Berkeley Heights 2011, ISBN 978-0-8379-7031-8 (Volume 1), ISBN 978-0-8379-7035-6 (complete work), ISSN 0083-9396 , p. 1802
- Who's Who 2012 . 164th edition. A & C Black, London 2011, ISBN 978-1-4081-4229-5 , pp. 965 .
- Catherine Nobes, Alison Lloyd and Mark Marsh: Alan Hall (1952–2015). In: Science . Volume 350, No. 6264, 2015, p. 1039, doi: 10.1126 / science.aad8407
Web links
- Alan Hall, PhD and autobiographical notes at Memorial Sloan-Kettering Cancer Center (mskcc.org); Retrieved February 13, 2011
Individual evidence
- ↑ Felberg Foundation prize winners (English) at feldbergfoundation.org; Retrieved February 12, 2011
- ↑ Royal Society Fellows at royalsociety.org; Retrieved February 12, 2011
- ^ Fondation Louis-Jeantet - Lauréats. In: jeantet.ch. Retrieved January 31, 2016 (French).
- ↑ Alan Hall PhD, FRS (English) at the Gairdner Foundation (gairdner.org); Retrieved December 15, 2012
| personal data | |
|---|---|
| SURNAME | Hall, Alan |
| BRIEF DESCRIPTION | British cell biologist |
| DATE OF BIRTH | May 19, 1952 |
| PLACE OF BIRTH | Barnsley , South Yorkshire |
| DATE OF DEATH | May 3, 2015 |