Antoine Gakeme first appeared at the U20 African Championships in Mauritius in 2009 at an international championship over 800 meters, but was eliminated in the run-up. His next international appearance was the World Championships in Moscow four years later . He survived the pre-run with a new best time and improved his time in the semifinals again to 1: 45.39 min, with which he narrowly missed the entry into the final as fourth of his run. Later he qualified for the African Championships in Marrakech. After a successful run-up, he reached the finish line in 1: 49.74 minutes in seventh place. Gakeme has been training in Spain since 2015. There he took part in the spring, among other things, in the Spanish indoor championships, where he was able to win over 1500 meters. He competed in Europe throughout the season. In July he ran a time of 1: 44.09 minutes in Madrid, which has been his best time ever since. He could not confirm this time at the World Championships in Beijing in August , which is why he, like two years before, was eliminated again in the semifinals. In the spring of 2016, Gakeme first competed at the World Indoor Championships in Portland. There he moved into the final, in which he ran a personal best indoor time of 1: 46.65 minutes, with which he became indoor vice world champion. In the course of the year he also qualified for the Summer Olympics in Rio de Janeiro. There he did not get beyond the lead.
In 2017 he took part in his third World Championships in London . As with his previous participations, he did not make it into the final again. In 2018 Gakeme competed at the World Indoor Championships in Birmingham. As fourth of his prelim, he missed making it into the final as fourth. In August he started at the African Championships in Nigeria. As in 2014, he made it into the final, in which he was only a hundredth of a second short of the bronze rank with a time of 1: 45.91 minutes, which the Moroccan Mostafa Smaili secured. In 2019, he missed participation in the World Championships in Doha.
Antoine Gakeme comes from the south-eastern province of Rutana in the central African state of Burundi. He lives in the Spanish city of Castellón de la Plana on the Mediterranean Sea, where he trains at the local Playas de Castellón FS .