Barry Trost
Barry M. Trost (born June 13, 1941 in Philadelphia ) is an American chemist and professor of chemistry at Stanford University .
life and work
He graduated from the University of Pennsylvania . For his dissertation on the structure and reactivity of enolate anions , he moved to the Massachusetts Institute of Technology in the group of Herbert O. House . He was a professor at the University of Wisconsin from 1965 to 1987 and then moved to Stanford University.
The Tsuji Trost Reaction and the Trost Ligand are named after him. According to his own statements, he is one of the 50 most frequently cited chemists in the world.
The research focus is on synthesis, whereby the development of new reactions and reagents as well as the development of a network of reactions (see also tandem reaction ) in order to build complex target molecules from simple molecules. For the development of new reactions the route of the so-called chemical enzymes is pursued, which are non-peptide transition metal-based catalysts with chemo-, regio- and enantioselective properties. Target molecules include ring compounds with more than six ring members produced by metal catalysis.
Honors, prizes and memberships (selection)
- 1967–69: Alfred P. Sloan Foundation Fellow
- 1977: ACS Award in Pure Chemistry
- 1980: Member of the National Academy of Sciences
- 1981-82: Centenary Lecturer of the Royal Society of Chemistry
- 1982: Member of the American Academy of Arts and Sciences
- 1983: Medal of the University of Helsinki
- Prize from the Alexander von Humboldt Foundation
- 1989: Arthur C. Cope Scholar Award
- 1990: Paul Janssen Prize for Creativity in Organic Synthesis
- 1994: Honorary doctorate from the University of Lyon
- 2001: Yamada Prize
- 2002: Nobel Laureate Signature Award for Graduate Education from the American Chemical Society
- 2013: Ryōji Noyori Prize
- 2014: Tetrahedron Prize
- 2014: August Wilhelm von Hofmann memorial coin
- 2015: Linus Pauling Award
- 2020: Sir Derek H. Barton Gold Medal
Publications (selection)
Reference books
- ML Crawley, BM Trost: Applications of Transition Metal Catalysis in Drug Discovery and Development. John Wiley & Sons, 2012, ISBN 1-118-30983-9 limited preview in Google Book Search
- BM Trost: Stereocontrolled Organic Synthesis. Blackwell Scientific Publications, 1994, ISBN 0-86542-833-6
- BM Trost, MF Semmelhack, I. Fleming: Comprehensive Organic Synthesis: Additions to and Substitutions at CC Pi-Bonds. Verlag Elsevier, 1991, ISBN 0-08-040595-9 limited preview in Google Book Search
- BM Trost: Problems in Spectroscopy , WA Benjamin Co., 1977
- BM Trost, LS Melvin: Sulfur Ylides - Emerging Synthetic Intermediates , Academic Press, 1975, ISBN 0-12-701060-2
Technical article
- BM Trost, K. Hirano: Highly Stereoselective Synthesis of α-Alkyl-α-Hydroxycarboxylic Acid Derivatives Catalyzed by a Dinuclear Zinc Complex. In: Angewandte Chemie (International edition). Volume 51, number 26, June 2012, pp. 6480–6483, doi: 10.1002 / anie.201201116 . PMID 22644705 .
- BM Trost, G. Dong: Total synthesis of bryostatin 16 using atom-economical and chemoselective approaches. In: Nature . Volume 456, number 7221, November 2008, pp. 485-488, doi: 10.1038 / nature07543 . PMID 19037312 . PMC 2728752 (free full text).
- BM Trost: Asymmetric catalysis: an enabling science. In: Proceedings of the National Academy of Sciences . Volume 101, Number 15, April 2004, pp. 5348-5355, doi: 10.1073 / pnas.0306715101 . PMID 14990801 . PMC 397384 (free full text). (Review).
- BM Trost: The atom economy - a search for synthetic efficiency. In: Science . Volume 254, Number 5037, December 1991, pp. 1471-1477, PMID 1962206 .
- BM Trost: Sculpting horizons in organic chemistry. In: Science . Volume 227, Number 4689, February 1985, pp. 908-916, PMID 3969569 .
- BM Trost: Selectivity: a key to synthetic efficiency. In: Science . Volume 219, Number 4582, January 1983, pp. 245-250, doi: 10.1126 / science.219.4582.245 . PMID 17798254 .
Web links
personal data | |
---|---|
SURNAME | Consolation, Barry |
ALTERNATIVE NAMES | Trost, Barry M. |
BRIEF DESCRIPTION | American chemist |
DATE OF BIRTH | June 13, 1941 |
PLACE OF BIRTH | Philadelphia |