Butyric anhydride

Structural formula
General
Surname	Butyric anhydride
other names	n -Butyric anhydride
Molecular formula	C 8 H 14 O 3
Brief description	colorless, malodorous liquid
External identifiers / databases
CAS number 106-31-0 EC number 203-383-4 ECHA InfoCard 100.003.077 PubChem 7798 Wikidata Q5003196
properties
Molar mass	158.20 g mol −1
Physical state	liquid
density	0.97 g cm −3
Melting point	−75 ° C
boiling point	198 ° C
Vapor pressure	0.4 mbar (20 ° C)
solubility	hydrolyzed in water and ethanol soluble in ether
Refractive index	1.413 (20 ° C)
safety instructions
GHS labeling of hazardous substances danger H and P phrases H: 314 EUH: 014 P: 280-305 + 351 + 338-310
Toxicological data	8790 mg kg −1 ( LD 50 ,  rat ,  oral )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

Butyric anhydride is a chemical compound from the group of carboxylic acid anhydrides .

Extraction and presentation

Butyric anhydride can be obtained by catalytic hydrogenation of crotonic acid or by reacting butyric acid or methyl butyrate with acetic anhydride or ketene .

properties

Butyric anhydride is a colorless, hardly flammable liquid with a foul odor, which hydrolyzes in water with violent reaction.

use

Butyric anhydride is used in the synthesis of dibutyrylchitin (a lipophilic chitin diester) and butyric acid ester derivatives of hyaluronic acid .

safety instructions

The vapors of butyric anhydride can form an explosive mixture with air ( flash point 88 ° C, ignition temperature 279 ° C).

Individual evidence

1. ↑ ^{a b c d e f g h i j k l} Entry on butyric anhydride in the GESTIS substance database of the IFA , accessed on July 23, 2016(JavaScript required) .
2. ↑ ^{a b c} Entry on butyric anhydride in the Hazardous Substances Data Bank , accessed on August 12, 2014.
3. ↑ ^{a b} Data sheet Butyric anhydride, purum, ≥97.0% (NT) from Sigma-Aldrich , accessed on August 12, 2014 ( PDF ).